MacKeigan JP - Search Results

1

Mitochondrial morphological features are associated with fission and fusion events.

Westrate LM, Drocco JA, Martin KR, Hlavacek WS, MacKeigan JP. Westrate LM, et al. Among authors: mackeigan jp. PLoS One. 2014 Apr 14;9(4):e95265. doi: 10.1371/journal.pone.0095265. eCollection 2014. PLoS One. 2014. PMID: 24733410 Free PMC article.

2

Identification of PTPsigma as an autophagic phosphatase.

Martin KR, Xu Y, Looyenga BD, Davis RJ, Wu CL, Tremblay ML, Xu HE, MacKeigan JP. Martin KR, et al. Among authors: mackeigan jp. J Cell Sci. 2011 Mar 1;124(Pt 5):812-9. doi: 10.1242/jcs.080341. Epub 2011 Feb 8. J Cell Sci. 2011. PMID: 21303930 Free PMC article.

3

Identification of a lysosomal pathway that modulates glucocorticoid signaling and the inflammatory response.

He Y, Xu Y, Zhang C, Gao X, Dykema KJ, Martin KR, Ke J, Hudson EA, Khoo SK, Resau JH, Alberts AS, MacKeigan JP, Furge KA, Xu HE. He Y, et al. Among authors: mackeigan jp. Sci Signal. 2011 Jul 5;4(180):ra44. doi: 10.1126/scisignal.2001450. Sci Signal. 2011. PMID: 21730326 Free PMC article.

4

Identification of small molecule inhibitors of PTPσ through an integrative virtual and biochemical approach.

Martin KR, Narang P, Xu Y, Kauffman AL, Petit J, Xu HE, Meurice N, MacKeigan JP. Martin KR, et al. Among authors: mackeigan jp. PLoS One. 2012;7(11):e50217. doi: 10.1371/journal.pone.0050217. Epub 2012 Nov 20. PLoS One. 2012. PMID: 23185579 Free PMC article.

5

Computational model for autophagic vesicle dynamics in single cells.

Martin KR, Barua D, Kauffman AL, Westrate LM, Posner RG, Hlavacek WS, Mackeigan JP. Martin KR, et al. Among authors: mackeigan jp. Autophagy. 2013 Jan;9(1):74-92. doi: 10.4161/auto.22532. Epub 2012 Nov 29. Autophagy. 2013. PMID: 23196898 Free PMC article.

6

Downregulation of the mitochondrial phosphatase PTPMT1 is sufficient to promote cancer cell death.

Niemi NM, Lanning NJ, Westrate LM, MacKeigan JP. Niemi NM, et al. Among authors: mackeigan jp. PLoS One. 2013;8(1):e53803. doi: 10.1371/journal.pone.0053803. Epub 2013 Jan 10. PLoS One. 2013. PMID: 23326511 Free PMC article.

7

Integrating virtual and biochemical screening for protein tyrosine phosphatase inhibitor discovery.

Martin KR, Narang P, Medina-Franco JL, Meurice N, MacKeigan JP. Martin KR, et al. Among authors: mackeigan jp. Methods. 2014 Jan 15;65(2):219-28. doi: 10.1016/j.ymeth.2013.08.013. Epub 2013 Aug 20. Methods. 2014. PMID: 23969317 Free PMC article.

8

Persistent mitochondrial hyperfusion promotes G2/M accumulation and caspase-dependent cell death.

Westrate LM, Sayfie AD, Burgenske DM, MacKeigan JP. Westrate LM, et al. Among authors: mackeigan jp. PLoS One. 2014 Mar 14;9(3):e91911. doi: 10.1371/journal.pone.0091911. eCollection 2014. PLoS One. 2014. PMID: 24632851 Free PMC article.

9

The pseudophosphatase MK-STYX physically and genetically interacts with the mitochondrial phosphatase PTPMT1.

Niemi NM, Sacoman JL, Westrate LM, Gaither LA, Lanning NJ, Martin KR, MacKeigan JP. Niemi NM, et al. Among authors: mackeigan jp. PLoS One. 2014 Apr 7;9(4):e93896. doi: 10.1371/journal.pone.0093896. eCollection 2014. PLoS One. 2014. PMID: 24709986 Free PMC article.

10

Development of potent autophagy inhibitors that sensitize oncogenic BRAF V600E mutant melanoma tumor cells to vemurafenib.

Goodall ML, Wang T, Martin KR, Kortus MG, Kauffman AL, Trent JM, Gately S, MacKeigan JP. Goodall ML, et al. Among authors: mackeigan jp. Autophagy. 2014 Jun;10(6):1120-36. doi: 10.4161/auto.28594. Autophagy. 2014. PMID: 24879157 Free PMC article.

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