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Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion.
Markovic DS, Vinnakota K, Chirasani S, Synowitz M, Raguet H, Stock K, Sliwa M, Lehmann S, Kälin R, van Rooijen N, Holmbeck K, Heppner FL, Kiwit J, Matyash V, Lehnardt S, Kaminska B, Glass R, Kettenmann H. Markovic DS, et al. Among authors: lehnardt s. Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12530-5. doi: 10.1073/pnas.0804273106. Epub 2009 Jul 15. Proc Natl Acad Sci U S A. 2009. PMID: 19617536 Free PMC article.
Toll-like receptor 2 mediates microglia/brain macrophage MT1-MMP expression and glioma expansion.
Vinnakota K, Hu F, Ku MC, Georgieva PB, Szulzewsky F, Pohlmann A, Waiczies S, Waiczies H, Niendorf T, Lehnardt S, Hanisch UK, Synowitz M, Markovic D, Wolf SA, Glass R, Kettenmann H. Vinnakota K, et al. Among authors: lehnardt s. Neuro Oncol. 2013 Nov;15(11):1457-68. doi: 10.1093/neuonc/not115. Epub 2013 Sep 5. Neuro Oncol. 2013. PMID: 24014382 Free PMC article.
Glioma-derived versican promotes tumor expansion via glioma-associated microglial/macrophages Toll-like receptor 2 signaling.
Hu F, Dzaye O, Hahn A, Yu Y, Scavetta RJ, Dittmar G, Kaczmarek AK, Dunning KR, Ricciardelli C, Rinnenthal JL, Heppner FL, Lehnardt S, Synowitz M, Wolf SA, Kettenmann H. Hu F, et al. Among authors: lehnardt s. Neuro Oncol. 2015 Feb;17(2):200-10. doi: 10.1093/neuonc/nou324. Epub 2014 Dec 1. Neuro Oncol. 2015. PMID: 25452390 Free PMC article.
let-7 MicroRNAs Regulate Microglial Function and Suppress Glioma Growth through Toll-Like Receptor 7.
Buonfiglioli A, Efe IE, Guneykaya D, Ivanov A, Huang Y, Orlowski E, Krüger C, Deisz RA, Markovic D, Flüh C, Newman AG, Schneider UC, Beule D, Wolf SA, Dzaye O, Gutmann DH, Semtner M, Kettenmann H, Lehnardt S. Buonfiglioli A, et al. Among authors: lehnardt s. Cell Rep. 2019 Dec 10;29(11):3460-3471.e7. doi: 10.1016/j.celrep.2019.11.029. Cell Rep. 2019. PMID: 31825829 Free article.
46 results