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The phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 is effective in inhibiting regrowth of tumour cells after cytotoxic therapy.
Hernlund E, Olofsson MH, Fayad W, Fryknäs M, Lesiak-Mieczkowska K, Zhang X, Brnjic S, Schmidt V, D'Arcy P, Sjöblom T, De Milito A, Larsson R, Linder S. Hernlund E, et al. Among authors: sjoblom t. Eur J Cancer. 2012 Feb;48(3):396-406. doi: 10.1016/j.ejca.2011.11.013. Epub 2011 Dec 7. Eur J Cancer. 2012. PMID: 22154651
U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.
Glimelius B, Melin B, Enblad G, Alafuzoff I, Beskow A, Ahlström H, Bill-Axelson A, Birgisson H, Björ O, Edqvist PH, Hansson T, Helleday T, Hellman P, Henriksson K, Hesselager G, Hultdin M, Häggman M, Höglund M, Jonsson H, Larsson C, Lindman H, Ljuslinder I, Mindus S, Nygren P, Pontén F, Riklund K, Rosenquist R, Sandin F, Schwenk JM, Stenling R, Stålberg K, Stålberg P, Sundström C, Thellenberg Karlsson C, Westermark B, Bergh A, Claesson-Welsh L, Palmqvist R, Sjöblom T. Glimelius B, et al. Among authors: sjoblom t. Acta Oncol. 2018 Feb;57(2):187-194. doi: 10.1080/0284186X.2017.1337926. Epub 2017 Jun 20. Acta Oncol. 2018. PMID: 28631533
Stroma-normalised vessel density predicts benefit from adjuvant fluorouracil-based chemotherapy in patients with stage II/III colon cancer.
Mezheyeuski A, Hrynchyk I, Herrera M, Karlberg M, Osterman E, Ragnhammar P, Edler D, Portyanko A, Ponten F, Sjöblom T, Glimelius B, Östman A. Mezheyeuski A, et al. Among authors: sjoblom t. Br J Cancer. 2019 Aug;121(4):303-311. doi: 10.1038/s41416-019-0519-1. Epub 2019 Jul 10. Br J Cancer. 2019. PMID: 31289351 Free PMC article.
Exploiting loss of heterozygosity for allele-selective colorectal cancer chemotherapy.
Rendo V, Stoimenov I, Mateus A, Sjöberg E, Svensson R, Gustavsson AL, Johansson L, Ng A, OʼBrien C, Giannakis M, Artursson P, Nygren P, Cheong I, Sjöblom T. Rendo V, et al. Among authors: sjoblom t. Nat Commun. 2020 Mar 11;11(1):1308. doi: 10.1038/s41467-020-15111-4. Nat Commun. 2020. PMID: 32161261 Free PMC article.
PDGF receptors as cancer drug targets.
Pietras K, Sjöblom T, Rubin K, Heldin CH, Ostman A. Pietras K, et al. Among authors: sjoblom t. Cancer Cell. 2003 May;3(5):439-43. doi: 10.1016/s1535-6108(03)00089-8. Cancer Cell. 2003. PMID: 12781361 Free article. Review. No abstract available.
STC1 expression by cancer-associated fibroblasts drives metastasis of colorectal cancer.
Peña C, Céspedes MV, Lindh MB, Kiflemariam S, Mezheyeuski A, Edqvist PH, Hägglöf C, Birgisson H, Bojmar L, Jirström K, Sandström P, Olsson E, Veerla S, Gallardo A, Sjöblom T, Chang AC, Reddel RR, Mangues R, Augsten M, Ostman A. Peña C, et al. Among authors: sjoblom t. Cancer Res. 2013 Feb 15;73(4):1287-97. doi: 10.1158/0008-5472.CAN-12-1875. Epub 2012 Dec 14. Cancer Res. 2013. PMID: 23243022
122 results