Salmena L - Search Results

1

Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein function.

Papa A, Wan L, Bonora M, Salmena L, Song MS, Hobbs RM, Lunardi A, Webster K, Ng C, Newton RH, Knoblauch N, Guarnerio J, Ito K, Turka LA, Beck AH, Pinton P, Bronson RT, Wei W, Pandolfi PP. Papa A, et al. Among authors: salmena l. Cell. 2014 Apr 24;157(3):595-610. doi: 10.1016/j.cell.2014.03.027. Cell. 2014. PMID: 24766807 Free PMC article.

2

Changing venues for tumour suppression: balancing destruction and localization by monoubiquitylation.

Salmena L, Pandolfi PP. Salmena L, et al. Nat Rev Cancer. 2007 Jun;7(6):409-13. doi: 10.1038/nrc2145. Epub 2007 May 17. Nat Rev Cancer. 2007. PMID: 17508027 Review.

3

Tenets of PTEN tumor suppression.

Salmena L, Carracedo A, Pandolfi PP. Salmena L, et al. Cell. 2008 May 2;133(3):403-14. doi: 10.1016/j.cell.2008.04.013. Cell. 2008. PMID: 18455982 Free article.

4

SnapShot: PTEN signaling pathways.

Carracedo A, Salmena L, Pandolfi PP. Carracedo A, et al. Among authors: salmena l. Cell. 2008 May 2;133(3):550.e1. doi: 10.1016/j.cell.2008.04.023. Cell. 2008. PMID: 18455993 Free article. No abstract available.

5

Aberrant Rheb-mediated mTORC1 activation and Pten haploinsufficiency are cooperative oncogenic events.

Nardella C, Chen Z, Salmena L, Carracedo A, Alimonti A, Egia A, Carver B, Gerald W, Cordon-Cardo C, Pandolfi PP. Nardella C, et al. Among authors: salmena l. Genes Dev. 2008 Aug 15;22(16):2172-7. doi: 10.1101/gad.1699608. Genes Dev. 2008. PMID: 18708577 Free PMC article.

6

The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network.

Song MS, Salmena L, Carracedo A, Egia A, Lo-Coco F, Teruya-Feldstein J, Pandolfi PP. Song MS, et al. Among authors: salmena l. Nature. 2008 Oct 9;455(7214):813-7. doi: 10.1038/nature07290. Epub 2008 Aug 20. Nature. 2008. PMID: 18716620 Free PMC article.

7

Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer.

Carracedo A, Ma L, Teruya-Feldstein J, Rojo F, Salmena L, Alimonti A, Egia A, Sasaki AT, Thomas G, Kozma SC, Papa A, Nardella C, Cantley LC, Baselga J, Pandolfi PP. Carracedo A, et al. Among authors: salmena l. J Clin Invest. 2008 Sep;118(9):3065-74. doi: 10.1172/JCI34739. J Clin Invest. 2008. PMID: 18725988 Free PMC article.

8

High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia.

Gutierrez A, Sanda T, Grebliunaite R, Carracedo A, Salmena L, Ahn Y, Dahlberg S, Neuberg D, Moreau LA, Winter SS, Larson R, Zhang J, Protopopov A, Chin L, Pandolfi PP, Silverman LB, Hunger SP, Sallan SE, Look AT. Gutierrez A, et al. Among authors: salmena l. Blood. 2009 Jul 16;114(3):647-50. doi: 10.1182/blood-2009-02-206722. Epub 2009 May 20. Blood. 2009. PMID: 19458356 Free PMC article.

9

Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signaling.

Gewinner C, Wang ZC, Richardson A, Teruya-Feldstein J, Etemadmoghadam D, Bowtell D, Barretina J, Lin WM, Rameh L, Salmena L, Pandolfi PP, Cantley LC. Gewinner C, et al. Among authors: salmena l. Cancer Cell. 2009 Aug 4;16(2):115-25. doi: 10.1016/j.ccr.2009.06.006. Cancer Cell. 2009. PMID: 19647222 Free PMC article.

10

Identification of the miR-106b~25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation.

Poliseno L, Salmena L, Riccardi L, Fornari A, Song MS, Hobbs RM, Sportoletti P, Varmeh S, Egia A, Fedele G, Rameh L, Loda M, Pandolfi PP. Poliseno L, et al. Among authors: salmena l. Sci Signal. 2010 Apr 13;3(117):ra29. doi: 10.1126/scisignal.2000594. Sci Signal. 2010. PMID: 20388916 Free PMC article.

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