Lanning NJ - Search Results

1

A mitochondrial RNAi screen defines cellular bioenergetic determinants and identifies an adenylate kinase as a key regulator of ATP levels.

Lanning NJ, Looyenga BD, Kauffman AL, Niemi NM, Sudderth J, DeBerardinis RJ, MacKeigan JP. Lanning NJ, et al. Cell Rep. 2014 May 8;7(3):907-17. doi: 10.1016/j.celrep.2014.03.065. Epub 2014 Apr 24. Cell Rep. 2014. PMID: 24767988 Free PMC article.

2

MK-STYX, a catalytically inactive phosphatase regulating mitochondrially dependent apoptosis.

Niemi NM, Lanning NJ, Klomp JA, Tait SW, Xu Y, Dykema KJ, Murphy LO, Gaither LA, Xu HE, Furge KA, Green DR, MacKeigan JP. Niemi NM, et al. Among authors: lanning nj. Mol Cell Biol. 2011 Apr;31(7):1357-68. doi: 10.1128/MCB.00788-10. Epub 2011 Jan 24. Mol Cell Biol. 2011. PMID: 21262771 Free PMC article.

3

Mitochondria in cancer: at the crossroads of life and death.

Fogg VC, Lanning NJ, Mackeigan JP. Fogg VC, et al. Among authors: lanning nj. Chin J Cancer. 2011 Aug;30(8):526-39. doi: 10.5732/cjc.011.10018. Chin J Cancer. 2011. PMID: 21801601 Free PMC article. Review.

4

Downregulation of the mitochondrial phosphatase PTPMT1 is sufficient to promote cancer cell death.

Niemi NM, Lanning NJ, Westrate LM, MacKeigan JP. Niemi NM, et al. Among authors: lanning nj. PLoS One. 2013;8(1):e53803. doi: 10.1371/journal.pone.0053803. Epub 2013 Jan 10. PLoS One. 2013. PMID: 23326511 Free PMC article.

5

The pseudophosphatase MK-STYX physically and genetically interacts with the mitochondrial phosphatase PTPMT1.

Niemi NM, Sacoman JL, Westrate LM, Gaither LA, Lanning NJ, Martin KR, MacKeigan JP. Niemi NM, et al. Among authors: lanning nj. PLoS One. 2014 Apr 7;9(4):e93896. doi: 10.1371/journal.pone.0093896. eCollection 2014. PLoS One. 2014. PMID: 24709986 Free PMC article.

6

DDK Promotes Tumor Chemoresistance and Survival via Multiple Pathways.

Sasi NK, Bhutkar A, Lanning NJ, MacKeigan JP, Weinreich M. Sasi NK, et al. Among authors: lanning nj. Neoplasia. 2017 May;19(5):439-450. doi: 10.1016/j.neo.2017.03.001. Epub 2017 Apr 25. Neoplasia. 2017. PMID: 28448802 Free PMC article.

7

Metabolic profiling of triple-negative breast cancer cells reveals metabolic vulnerabilities.

Lanning NJ, Castle JP, Singh SJ, Leon AN, Tovar EA, Sanghera A, MacKeigan JP, Filipp FV, Graveel CR. Lanning NJ, et al. Cancer Metab. 2017 Aug 22;5:6. doi: 10.1186/s40170-017-0168-x. eCollection 2017. Cancer Metab. 2017. PMID: 28852500 Free PMC article.

8

LRRK2 deficiency impairs trans-Golgi to lysosome trafficking and endocytic cargo degradation in human renal proximal tubule epithelial cells.

Lanning NJ, VanOpstall C, Goodall ML, MacKeigan JP, Looyenga BD. Lanning NJ, et al. Am J Physiol Renal Physiol. 2018 Nov 1;315(5):F1465-F1477. doi: 10.1152/ajprenal.00009.2018. Epub 2018 Aug 8. Am J Physiol Renal Physiol. 2018. PMID: 30089035 Free PMC article.

9

Unique Metabolic Contexts Sensitize Cancer Cells and Discriminate between Glycolytic Tumor Types.

Chacon-Barahona JA, MacKeigan JP, Lanning NJ. Chacon-Barahona JA, et al. Among authors: lanning nj. Cancers (Basel). 2023 Feb 11;15(4):1158. doi: 10.3390/cancers15041158. Cancers (Basel). 2023. PMID: 36831501 Free PMC article.

10

Phosphorylation of OXPHOS Machinery Subunits: Functional Implications in Cell Biology and Disease.

Castellanos E, Lanning NJ. Castellanos E, et al. Among authors: lanning nj. Yale J Biol Med. 2019 Sep 20;92(3):523-531. eCollection 2019 Sep. Yale J Biol Med. 2019. PMID: 31543713 Free PMC article. Review.

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