Priego EM - Search Results

1

Novel colchicine-site binders with a cyclohexanedione scaffold identified through a ligand-based virtual screening approach.

Canela MD, Pérez-Pérez MJ, Noppen S, Sáez-Calvo G, Díaz JF, Camarasa MJ, Liekens S, Priego EM. Canela MD, et al. Among authors: priego em. J Med Chem. 2014 May 22;57(10):3924-38. doi: 10.1021/jm401939g. Epub 2014 May 9. J Med Chem. 2014. PMID: 24773591 Free article.

2

Anti-angiogenic activity of a novel multi-substrate analogue inhibitor of thymidine phosphorylase.

Liekens S, Bilsen F, De Clercq E, Priego EM, Camarasa MJ, Pérez-Pérez MJ, Balzarini J. Liekens S, et al. Among authors: priego em. FEBS Lett. 2002 Jan 2;510(1-2):83-8. doi: 10.1016/s0014-5793(01)03233-1. FEBS Lett. 2002. PMID: 11755536 Free article.

3

Pyrido[2,1-f]purine-2,4-dione derivatives as a novel class of highly potent human A(3) adenosine receptor antagonists.

Priego EM, von Frijtag Drabbe Kuenzel J, IJzerman AP, Camarasa MJ, Pérez-Pérez MJ. Priego EM, et al. J Med Chem. 2002 Aug 1;45(16):3337-44. doi: 10.1021/jm0208469. J Med Chem. 2002. PMID: 12139445

4

Towards new thymidine phosphorylase/PD-ECGF inhibitors based on the transition state of the enzyme reaction.

Priego EM, Mendieta J, Gago F, Balzarini J, De Clercq E, Camarasa MJ, Pérez-Pérez MJ. Priego EM, et al. Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):951-3. doi: 10.1081/NCN-120022693. Nucleosides Nucleotides Nucleic Acids. 2003. PMID: 14565319

5

Role of histidine-85 in the catalytic mechanism of thymidine phosphorylase as assessed by targeted molecular dynamics simulations and quantum mechanical calculations.

Mendieta J, Martín-Santamaría S, Priego EM, Balzarini J, Camarasa MJ, Pérez-Pérez MJ, Gago F. Mendieta J, et al. Among authors: priego em. Biochemistry. 2004 Jan 20;43(2):405-14. doi: 10.1021/bi034793o. Biochemistry. 2004. PMID: 14717594

6

Synthesis and evaluation of thymine-derived carboxamides against mitochondrial thymidine kinase (TK-2) and related enzymes.

Priego EM, Balzarini J, Karlsson A, Camarasa MJ, Pérez-Pérez MJ. Priego EM, et al. Bioorg Med Chem. 2004 Oct 1;12(19):5079-90. doi: 10.1016/j.bmc.2004.07.036. Bioorg Med Chem. 2004. PMID: 15351391

7

Mitochondrial thymidine kinase inhibitors.

Pérez-Pérez MJ, Hernández AI, Priego EM, Rodríguez-Barrios F, Gago F, Camarasa MJ, Balzarini J. Pérez-Pérez MJ, et al. Among authors: priego em. Curr Top Med Chem. 2005;5(13):1205-19. doi: 10.2174/156802605774463097. Curr Top Med Chem. 2005. PMID: 16305527 Review.

8

Thymidine phosphorylase inhibitors: recent developments and potential therapeutic applications.

Pérez-Pérez MJ, Priego EM, Hernández AI, Camarasa MJ, Balzarini J, Liekens S. Pérez-Pérez MJ, et al. Among authors: priego em. Mini Rev Med Chem. 2005 Dec;5(12):1113-23. doi: 10.2174/138955705774933301. Mini Rev Med Chem. 2005. PMID: 16375757 Review.

9

5'-O-tritylated nucleoside derivatives: inhibition of thymidine phosphorylase and angiogenesis.

Liekens S, Bronckaers A, Hernández AI, Priego EM, Casanova E, Camarasa MJ, Pérez-Pérez MJ, Balzarini J. Liekens S, et al. Among authors: priego em. Mol Pharmacol. 2006 Aug;70(2):501-9. doi: 10.1124/mol.105.021188. Epub 2006 May 4. Mol Pharmacol. 2006. PMID: 16675660

10

5'-O-tritylinosine and analogues as allosteric inhibitors of human thymidine phosphorylase.

Casanova E, Hernandez AI, Priego EM, Liekens S, Camarasa MJ, Balzarini J, Pérez-Pérez MJ. Casanova E, et al. Among authors: priego em. J Med Chem. 2006 Sep 7;49(18):5562-70. doi: 10.1021/jm0605379. J Med Chem. 2006. PMID: 16942029

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