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Rad50-CARD9 interactions link cytosolic DNA sensing to IL-1β production.
Roth S, Rottach A, Lotz-Havla AS, Laux V, Muschaweckh A, Gersting SW, Muntau AC, Hopfner KP, Jin L, Vanness K, Petrini JH, Drexler I, Leonhardt H, Ruland J. Roth S, et al. Nat Immunol. 2014 Jun;15(6):538-45. doi: 10.1038/ni.2888. Epub 2014 Apr 28. Nat Immunol. 2014. PMID: 24777530 Free PMC article.
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production.
Poeck H, Bscheider M, Gross O, Finger K, Roth S, Rebsamen M, Hannesschläger N, Schlee M, Rothenfusser S, Barchet W, Kato H, Akira S, Inoue S, Endres S, Peschel C, Hartmann G, Hornung V, Ruland J. Poeck H, et al. Among authors: roth s. Nat Immunol. 2010 Jan;11(1):63-9. doi: 10.1038/ni.1824. Epub 2009 Nov 15. Nat Immunol. 2010. PMID: 19915568
Caspase-8: clipping off RIG-I signaling.
Roth S, Ruland J. Roth S, et al. Immunity. 2011 Mar 25;34(3):283-5. doi: 10.1016/j.immuni.2011.03.011. Immunity. 2011. PMID: 21435580 Free article.
RIG-I detects infection with live Listeria by sensing secreted bacterial nucleic acids.
Abdullah Z, Schlee M, Roth S, Mraheil MA, Barchet W, Böttcher J, Hain T, Geiger S, Hayakawa Y, Fritz JH, Civril F, Hopfner KP, Kurts C, Ruland J, Hartmann G, Chakraborty T, Knolle PA. Abdullah Z, et al. Among authors: roth s. EMBO J. 2012 Nov 5;31(21):4153-64. doi: 10.1038/emboj.2012.274. Epub 2012 Oct 12. EMBO J. 2012. PMID: 23064150 Free PMC article.
Vav Proteins Are Key Regulators of Card9 Signaling for Innate Antifungal Immunity.
Roth S, Bergmann H, Jaeger M, Yeroslaviz A, Neumann K, Koenig PA, Prazeres da Costa C, Vanes L, Kumar V, Johnson M, Menacho-Márquez M, Habermann B, Tybulewicz VL, Netea M, Bustelo XR, Ruland J. Roth S, et al. Cell Rep. 2016 Dec 6;17(10):2572-2583. doi: 10.1016/j.celrep.2016.11.018. Cell Rep. 2016. PMID: 27926862 Free PMC article.
Dynamic landscape of pancreatic carcinogenesis reveals early molecular networks of malignancy.
Kong B, Bruns P, Behler NA, Chang L, Schlitter AM, Cao J, Gewies A, Ruland J, Fritzsche S, Valkovskaya N, Jian Z, Regel I, Raulefs S, Irmler M, Beckers J, Friess H, Erkan M, Mueller NS, Roth S, Hackert T, Esposito I, Theis FJ, Kleeff J, Michalski CW. Kong B, et al. Among authors: roth s. Gut. 2018 Jan;67(1):146-156. doi: 10.1136/gutjnl-2015-310913. Epub 2016 Sep 19. Gut. 2018. PMID: 27646934
2,510 results