Wang H - Search Results

1

Global CNS transduction of adult mice by intravenously delivered rAAVrh.8 and rAAVrh.10 and nonhuman primates by rAAVrh.10.

Yang B, Li S, Wang H, Guo Y, Gessler DJ, Cao C, Su Q, Kramer J, Zhong L, Ahmed SS, Zhang H, He R, Desrosiers RC, Brown R, Xu Z, Gao G. Yang B, et al. Among authors: wang h. Mol Ther. 2014 Jul;22(7):1299-1309. doi: 10.1038/mt.2014.68. Epub 2014 Apr 30. Mol Ther. 2014. PMID: 24781136 Free PMC article.

2

Several rAAV vectors efficiently cross the blood-brain barrier and transduce neurons and astrocytes in the neonatal mouse central nervous system.

Zhang H, Yang B, Mu X, Ahmed SS, Su Q, He R, Wang H, Mueller C, Sena-Esteves M, Brown R, Xu Z, Gao G. Zhang H, et al. Among authors: wang h. Mol Ther. 2011 Aug;19(8):1440-8. doi: 10.1038/mt.2011.98. Epub 2011 May 24. Mol Ther. 2011. PMID: 21610699 Free PMC article.

3

Widespread spinal cord transduction by intrathecal injection of rAAV delivers efficacious RNAi therapy for amyotrophic lateral sclerosis.

Wang H, Yang B, Qiu L, Yang C, Kramer J, Su Q, Guo Y, Brown RH Jr, Gao G, Xu Z. Wang H, et al. Hum Mol Genet. 2014 Feb 1;23(3):668-81. doi: 10.1093/hmg/ddt454. Epub 2013 Sep 18. Hum Mol Genet. 2014. PMID: 24108104 Free PMC article.

4

Partial loss of TDP-43 function causes phenotypes of amyotrophic lateral sclerosis.

Yang C, Wang H, Qiao T, Yang B, Aliaga L, Qiu L, Tan W, Salameh J, McKenna-Yasek DM, Smith T, Peng L, Moore MJ, Brown RH Jr, Cai H, Xu Z. Yang C, et al. Among authors: wang h. Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):E1121-9. doi: 10.1073/pnas.1322641111. Epub 2014 Mar 10. Proc Natl Acad Sci U S A. 2014. PMID: 24616503 Free PMC article.

5

Nerve injection of viral vectors efficiently transfers transgenes into motor neurons and delivers RNAi therapy against ALS.

Wu R, Wang H, Xia X, Zhou H, Liu C, Castro M, Xu Z. Wu R, et al. Among authors: wang h. Antioxid Redox Signal. 2009 Jul;11(7):1523-34. doi: 10.1089/ars.2009.2618. Antioxid Redox Signal. 2009. PMID: 19344276 Free PMC article.

6

Widespread aggregation of mutant VAPB associated with ALS does not cause motor neuron degeneration or modulate mutant SOD1 aggregation and toxicity in mice.

Qiu L, Qiao T, Beers M, Tan W, Wang H, Yang B, Xu Z. Qiu L, et al. Among authors: wang h. Mol Neurodegener. 2013 Jan 3;8:1. doi: 10.1186/1750-1326-8-1. Mol Neurodegener. 2013. PMID: 23281774 Free PMC article.

7

A construct with fluorescent indicators for conditional expression of miRNA.

Qiu L, Wang H, Xia X, Zhou H, Xu Z. Qiu L, et al. Among authors: wang h. BMC Biotechnol. 2008 Oct 7;8:77. doi: 10.1186/1472-6750-8-77. BMC Biotechnol. 2008. PMID: 18840295 Free PMC article.

8

Low-level overexpression of wild type TDP-43 causes late-onset, progressive neurodegeneration and paralysis in mice.

Yang C, Qiao T, Yu J, Wang H, Guo Y, Salameh J, Metterville J, Parsi S, Yusuf I, Brown RH, Cai H, Xu Z. Yang C, et al. Among authors: wang h. PLoS One. 2022 Feb 3;17(2):e0255710. doi: 10.1371/journal.pone.0255710. eCollection 2022. PLoS One. 2022. PMID: 35113871 Free PMC article.

9

Therapeutic gene silencing delivered by a chemically modified small interfering RNA against mutant SOD1 slows amyotrophic lateral sclerosis progression.

Wang H, Ghosh A, Baigude H, Yang CS, Qiu L, Xia X, Zhou H, Rana TM, Xu Z. Wang H, et al. J Biol Chem. 2008 Jun 6;283(23):15845-52. doi: 10.1074/jbc.M800834200. Epub 2008 Mar 26. J Biol Chem. 2008. PMID: 18367449 Free PMC article.

10

Development of Excipient-Free Freeze-Dryable Unimolecular Hyperstar Polymers for Efficient siRNA Silencing.

Zhao L, Wu X, Wang X, Duan C, Wang H, Punjabi A, Zhao Y, Zhang Y, Xu Z, Gao H, Han G. Zhao L, et al. Among authors: wang x, wang h. ACS Macro Lett. 2017 Jul 18;6(7):700-704. doi: 10.1021/acsmacrolett.7b00242. Epub 2017 Jun 19. ACS Macro Lett. 2017. PMID: 35650873

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