Gaiddon C - Search Results

1

Subcellular localization and transport kinetics of ruthenium organometallic anticancer compounds in living cells: a dose-dependent role for amino acid and iron transporters.

Klajner M, Licona C, Fetzer L, Hebraud P, Mellitzer G, Pfeffer M, Harlepp S, Gaiddon C. Klajner M, et al. Among authors: gaiddon c. Inorg Chem. 2014 May 19;53(10):5150-8. doi: 10.1021/ic500250e. Epub 2014 May 1. Inorg Chem. 2014. PMID: 24786362

2

Ruthenium (II)-derived organometallic compounds induce cytostatic and cytotoxic effects on mammalian cancer cell lines through p53-dependent and p53-independent mechanisms.

Gaiddon C, Jeannequin P, Bischoff P, Pfeffer M, Sirlin C, Loeffler JP. Gaiddon C, et al. J Pharmacol Exp Ther. 2005 Dec;315(3):1403-11. doi: 10.1124/jpet.105.089342. Epub 2005 Sep 16. J Pharmacol Exp Ther. 2005. PMID: 16169939

3

A ruthenium-containing organometallic compound reduces tumor growth through induction of the endoplasmic reticulum stress gene CHOP.

Meng X, Leyva ML, Jenny M, Gross I, Benosman S, Fricker B, Harlepp S, Hébraud P, Boos A, Wlosik P, Bischoff P, Sirlin C, Pfeffer M, Loeffler JP, Gaiddon C. Meng X, et al. Among authors: gaiddon c. Cancer Res. 2009 Jul 1;69(13):5458-66. doi: 10.1158/0008-5472.CAN-08-4408. Epub 2009 Jun 23. Cancer Res. 2009. PMID: 19549908

4

DNA binding to an anticancer organo-ruthenium complex.

Klajner M, Hebraud P, Sirlin C, Gaiddon C, Harlepp S. Klajner M, et al. Among authors: gaiddon c. J Phys Chem B. 2010 Nov 11;114(44):14041-7. doi: 10.1021/jp1044783. J Phys Chem B. 2010. PMID: 20961087

5

Library of second-generation cycloruthenated compounds and evaluation of their biological properties as potential anticancer drugs: passing the nanomolar barrier.

Fetzer L, Boff B, Ali M, Xiangjun M, Collin JP, Sirlin C, Gaiddon C, Pfeffer M. Fetzer L, et al. Among authors: gaiddon c. Dalton Trans. 2011 Sep 21;40(35):8869-78. doi: 10.1039/c1dt10322a. Epub 2011 Aug 12. Dalton Trans. 2011. PMID: 21837342

6

Complex regulation of p73 isoforms after alteration of amyloid precursor polypeptide (APP) function and DNA damage in neurons.

Benosman S, Meng X, Von Grabowiecki Y, Palamiuc L, Hritcu L, Gross I, Mellitzer G, Taya Y, Loeffler JP, Gaiddon C. Benosman S, et al. Among authors: gaiddon c. J Biol Chem. 2011 Dec 16;286(50):43013-25. doi: 10.1074/jbc.M111.261271. Epub 2011 Oct 14. J Biol Chem. 2011. PMID: 22002055 Free PMC article.

7

Induction of caspase 8 and reactive oxygen species by ruthenium-derived anticancer compounds with improved water solubility and cytotoxicity.

Vidimar V, Meng X, Klajner M, Licona C, Fetzer L, Harlepp S, Hébraud P, Sidhoum M, Sirlin C, Loeffler JP, Mellitzer G, Sava G, Pfeffer M, Gaiddon C. Vidimar V, et al. Among authors: gaiddon c. Biochem Pharmacol. 2012 Dec 1;84(11):1428-36. doi: 10.1016/j.bcp.2012.08.022. Epub 2012 Sep 1. Biochem Pharmacol. 2012. PMID: 22964219

8

Cancer cell cytotoxicity of cyclometalated compounds obtained with osmium(II) complexes.

Boff B, Gaiddon C, Pfeffer M. Boff B, et al. Among authors: gaiddon c. Inorg Chem. 2013 Mar 4;52(5):2705-15. doi: 10.1021/ic302779q. Epub 2013 Feb 21. Inorg Chem. 2013. PMID: 23427955

9

Discovery and investigation of anticancer ruthenium-arene Schiff-base complexes via water-promoted combinatorial three-component assembly.

Chow MJ, Licona C, Yuan Qiang Wong D, Pastorin G, Gaiddon C, Ang WH. Chow MJ, et al. Among authors: gaiddon c. J Med Chem. 2014 Jul 24;57(14):6043-59. doi: 10.1021/jm500455p. Epub 2014 Jul 15. J Med Chem. 2014. PMID: 25023617

10

Regulation of a Notch3-Hes1 pathway and protective effect by a tocopherol-omega alkanol chain derivative in muscle atrophy.

von Grabowiecki Y, Licona C, Palamiuc L, Abreu P, Vidimar V, Coowar D, Mellitzer G, Gaiddon C. von Grabowiecki Y, et al. Among authors: gaiddon c. J Pharmacol Exp Ther. 2015 Jan;352(1):23-32. doi: 10.1124/jpet.114.216879. Epub 2014 Oct 17. J Pharmacol Exp Ther. 2015. PMID: 25326132

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