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Key tumor suppressor genes inactivated by "greater promoter" methylation and somatic mutations in head and neck cancer.
Guerrero-Preston R, Michailidi C, Marchionni L, Pickering CR, Frederick MJ, Myers JN, Yegnasubramanian S, Hadar T, Noordhuis MG, Zizkova V, Fertig E, Agrawal N, Westra W, Koch W, Califano J, Velculescu VE, Sidransky D. Guerrero-Preston R, et al. Among authors: agrawal n. Epigenetics. 2014 Jul;9(7):1031-46. doi: 10.4161/epi.29025. Epub 2014 May 1. Epigenetics. 2014. PMID: 24786473 Free PMC article.
Activation of the NOTCH pathway in head and neck cancer.
Sun W, Gaykalova DA, Ochs MF, Mambo E, Arnaoutakis D, Liu Y, Loyo M, Agrawal N, Howard J, Li R, Ahn S, Fertig E, Sidransky D, Houghton J, Buddavarapu K, Sanford T, Choudhary A, Darden W, Adai A, Latham G, Bishop J, Sharma R, Westra WH, Hennessey P, Chung CH, Califano JA. Sun W, et al. Among authors: agrawal n. Cancer Res. 2014 Feb 15;74(4):1091-104. doi: 10.1158/0008-5472.CAN-13-1259. Epub 2013 Dec 18. Cancer Res. 2014. PMID: 24351288 Free PMC article.
Human papillomavirus status of head and neck cancer as determined in cytologic specimens using the hybrid-capture 2 assay.
Smith DF, Maleki Z, Coughlan D, Gooi Z, Akpeng B, Ogawa T, Bishop JA, Frick KD, Agrawal N, Gourin CG, Ha PK, Koch WM, Richmon JD, Westra WH, Pai SI. Smith DF, et al. Among authors: agrawal n. Oral Oncol. 2014 Jun;50(6):600-4. doi: 10.1016/j.oraloncology.2014.02.011. Epub 2014 Mar 12. Oral Oncol. 2014. PMID: 24630260 Free PMC article.
Clinical, genomic, and metagenomic characterization of oral tongue squamous cell carcinoma in patients who do not smoke.
Li R, Faden DL, Fakhry C, Langelier C, Jiao Y, Wang Y, Wilkerson MD, Pedamallu CS, Old M, Lang J, Loyo M, Ahn SM, Tan M, Gooi Z, Chan J, Richmon J, Wood LD, Hruban RH, Bishop J, Westra WH, Chung CH, Califano J, Gourin CG, Bettegowda C, Meyerson M, Papadopoulos N, Kinzler KW, Vogelstein B, DeRisi JL, Koch WM, Agrawal N. Li R, et al. Among authors: agrawal n. Head Neck. 2015 Nov;37(11):1642-9. doi: 10.1002/hed.23807. Epub 2014 Aug 23. Head Neck. 2015. PMID: 24954188 Free PMC article.
Characterization of HPV and host genome interactions in primary head and neck cancers.
Parfenov M, Pedamallu CS, Gehlenborg N, Freeman SS, Danilova L, Bristow CA, Lee S, Hadjipanayis AG, Ivanova EV, Wilkerson MD, Protopopov A, Yang L, Seth S, Song X, Tang J, Ren X, Zhang J, Pantazi A, Santoso N, Xu AW, Mahadeshwar H, Wheeler DA, Haddad RI, Jung J, Ojesina AI, Issaeva N, Yarbrough WG, Hayes DN, Grandis JR, El-Naggar AK, Meyerson M, Park PJ, Chin L, Seidman JG, Hammerman PS, Kucherlapati R; Cancer Genome Atlas Network. Parfenov M, et al. Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):15544-9. doi: 10.1073/pnas.1416074111. Epub 2014 Oct 13. Proc Natl Acad Sci U S A. 2014. PMID: 25313082 Free PMC article.
Notch1 mutations are drivers of oral tumorigenesis.
Izumchenko E, Sun K, Jones S, Brait M, Agrawal N, Koch W, McCord CL, Riley DR, Angiuoli SV, Velculescu VE, Jiang WW, Sidransky D. Izumchenko E, et al. Among authors: agrawal n. Cancer Prev Res (Phila). 2015 Apr;8(4):277-286. doi: 10.1158/1940-6207.CAPR-14-0257. Epub 2014 Nov 18. Cancer Prev Res (Phila). 2015. PMID: 25406187 Free PMC article.
Tadalafil augments tumor specific immunity in patients with head and neck squamous cell carcinoma.
Califano JA, Khan Z, Noonan KA, Rudraraju L, Zhang Z, Wang H, Goodman S, Gourin CG, Ha PK, Fakhry C, Saunders J, Levine M, Tang M, Neuner G, Richmon JD, Blanco R, Agrawal N, Koch WM, Marur S, Weed DT, Serafini P, Borrello I. Califano JA, et al. Among authors: agrawal n. Clin Cancer Res. 2015 Jan 1;21(1):30-8. doi: 10.1158/1078-0432.CCR-14-1716. Clin Cancer Res. 2015. PMID: 25564570 Free PMC article. Clinical Trial.
Cleaved NOTCH1 Expression Pattern in Head and Neck Squamous Cell Carcinoma Is Associated with NOTCH1 Mutation, HPV Status, and High-Risk Features.
Rettig EM, Chung CH, Bishop JA, Howard JD, Sharma R, Li RJ, Douville C, Karchin R, Izumchenko E, Sidransky D, Koch W, Califano J, Agrawal N, Fakhry C. Rettig EM, et al. Among authors: agrawal n. Cancer Prev Res (Phila). 2015 Apr;8(4):287-95. doi: 10.1158/1940-6207.CAPR-14-0366. Epub 2015 Jan 29. Cancer Prev Res (Phila). 2015. PMID: 25633867 Free PMC article.
1,740 results