Galvagnion C - Search Results

1

Solution conditions determine the relative importance of nucleation and growth processes in α-synuclein aggregation.

Buell AK, Galvagnion C, Gaspar R, Sparr E, Vendruscolo M, Knowles TP, Linse S, Dobson CM. Buell AK, et al. Among authors: galvagnion c. Proc Natl Acad Sci U S A. 2014 May 27;111(21):7671-6. doi: 10.1073/pnas.1315346111. Epub 2014 May 9. Proc Natl Acad Sci U S A. 2014. PMID: 24817693 Free PMC article.

2

Direct observation of heterogeneous amyloid fibril growth kinetics via two-color super-resolution microscopy.

Pinotsi D, Buell AK, Galvagnion C, Dobson CM, Kaminski Schierle GS, Kaminski CF. Pinotsi D, et al. Among authors: galvagnion c. Nano Lett. 2014 Jan 8;14(1):339-45. doi: 10.1021/nl4041093. Epub 2013 Dec 11. Nano Lett. 2014. PMID: 24303845 Free PMC article.

3

Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation.

Galvagnion C, Buell AK, Meisl G, Michaels TC, Vendruscolo M, Knowles TP, Dobson CM. Galvagnion C, et al. Nat Chem Biol. 2015 Mar;11(3):229-34. doi: 10.1038/nchembio.1750. Epub 2015 Feb 2. Nat Chem Biol. 2015. PMID: 25643172 Free PMC article.

4

[Fundamental mechanisms of amyloid fibril formation by alpha-synuclein in Parkinson's disease: quantitative modelling].

Galvagnion C, Buell AK. Galvagnion C, et al. Med Sci (Paris). 2015 Jun-Jul;31(6-7):597-600. doi: 10.1051/medsci/20153106008. Epub 2015 Jul 7. Med Sci (Paris). 2015. PMID: 26152159 Free article. French. No abstract available.

5

Chemical properties of lipids strongly affect the kinetics of the membrane-induced aggregation of α-synuclein.

Galvagnion C, Brown JW, Ouberai MM, Flagmeier P, Vendruscolo M, Buell AK, Sparr E, Dobson CM. Galvagnion C, et al. Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):7065-70. doi: 10.1073/pnas.1601899113. Epub 2016 Jun 13. Proc Natl Acad Sci U S A. 2016. PMID: 27298346 Free PMC article.

6

Mutations associated with familial Parkinson's disease alter the initiation and amplification steps of α-synuclein aggregation.

Flagmeier P, Meisl G, Vendruscolo M, Knowles TP, Dobson CM, Buell AK, Galvagnion C. Flagmeier P, et al. Among authors: galvagnion c. Proc Natl Acad Sci U S A. 2016 Sep 13;113(37):10328-33. doi: 10.1073/pnas.1604645113. Epub 2016 Aug 29. Proc Natl Acad Sci U S A. 2016. PMID: 27573854 Free PMC article.

7

A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity.

Perni M, Galvagnion C, Maltsev A, Meisl G, Müller MB, Challa PK, Kirkegaard JB, Flagmeier P, Cohen SI, Cascella R, Chen SW, Limbocker R, Sormanni P, Heller GT, Aprile FA, Cremades N, Cecchi C, Chiti F, Nollen EA, Knowles TP, Vendruscolo M, Bax A, Zasloff M, Dobson CM. Perni M, et al. Among authors: galvagnion c. Proc Natl Acad Sci U S A. 2017 Feb 7;114(6):E1009-E1017. doi: 10.1073/pnas.1610586114. Epub 2017 Jan 17. Proc Natl Acad Sci U S A. 2017. PMID: 28096355 Free PMC article.

8

Lipid Dynamics and Phase Transition within α-Synuclein Amyloid Fibrils.

Galvagnion C, Topgaard D, Makasewicz K, Buell AK, Linse S, Sparr E, Dobson CM. Galvagnion C, et al. J Phys Chem Lett. 2019 Dec 19;10(24):7872-7877. doi: 10.1021/acs.jpclett.9b03005. Epub 2019 Dec 6. J Phys Chem Lett. 2019. PMID: 31790267 Free PMC article.

9

β-Synuclein suppresses both the initiation and amplification steps of α-synuclein aggregation via competitive binding to surfaces.

Brown JW, Buell AK, Michaels TC, Meisl G, Carozza J, Flagmeier P, Vendruscolo M, Knowles TP, Dobson CM, Galvagnion C. Brown JW, et al. Among authors: galvagnion c. Sci Rep. 2016 Nov 3;6:36010. doi: 10.1038/srep36010. Sci Rep. 2016. PMID: 27808107 Free PMC article.

10

Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson's disease.

Tóth G, Gardai SJ, Zago W, Bertoncini CW, Cremades N, Roy SL, Tambe MA, Rochet JC, Galvagnion C, Skibinski G, Finkbeiner S, Bova M, Regnstrom K, Chiou SS, Johnston J, Callaway K, Anderson JP, Jobling MF, Buell AK, Yednock TA, Knowles TP, Vendruscolo M, Christodoulou J, Dobson CM, Schenk D, McConlogue L. Tóth G, et al. Among authors: galvagnion c. PLoS One. 2014 Feb 14;9(2):e87133. doi: 10.1371/journal.pone.0087133. eCollection 2014. PLoS One. 2014. PMID: 24551051 Free PMC article.

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