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High expression of C5L2 correlates with high proinflammatory cytokine expression in advanced human atherosclerotic plaques.
Vijayan S, Asare Y, Grommes J, Soehnlein O, Lutgens E, Shagdarsuren G, Togtokh A, Jacobs MJ, Fischer JW, Bernhagen J, Weber C, Schober A, Shagdarsuren E. Vijayan S, et al. Among authors: lutgens e. Am J Pathol. 2014 Jul;184(7):2123-33. doi: 10.1016/j.ajpath.2014.04.004. Epub 2014 May 9. Am J Pathol. 2014. PMID: 24819959 Free article.
The CD40-TRAF6 axis is the key regulator of the CD40/CD40L system in neointima formation and arterial remodeling.
Donners MM, Beckers L, Lievens D, Munnix I, Heemskerk J, Janssen BJ, Wijnands E, Cleutjens J, Zernecke A, Weber C, Ahonen CL, Benbow U, Newby AC, Noelle RJ, Daemen MJ, Lutgens E. Donners MM, et al. Among authors: lutgens e. Blood. 2008 May 1;111(9):4596-604. doi: 10.1182/blood-2007-05-088906. Epub 2008 Jan 14. Blood. 2008. PMID: 18195092 Free PMC article.
Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile.
Lutgens E, Lievens D, Beckers L, Wijnands E, Soehnlein O, Zernecke A, Seijkens T, Engel D, Cleutjens J, Keller AM, Naik SH, Boon L, Oufella HA, Mallat Z, Ahonen CL, Noelle RJ, de Winther MP, Daemen MJ, Biessen EA, Weber C. Lutgens E, et al. J Exp Med. 2010 Feb 15;207(2):391-404. doi: 10.1084/jem.20091293. Epub 2010 Jan 25. J Exp Med. 2010. PMID: 20100871 Free PMC article.
245 results