Nieman MT - Search Results

1

Platelet specific promoters are insufficient to express protease activated receptor 1 (PAR1) transgene in mouse platelets.

Arachiche A, de la Fuente M, Nieman MT. Arachiche A, et al. Among authors: nieman mt. PLoS One. 2014 May 15;9(5):e97724. doi: 10.1371/journal.pone.0097724. eCollection 2014. PLoS One. 2014. PMID: 24830314 Free PMC article.

2

Mice with Reduced PAR4 Reactivity show Decreased Venous Thrombosis and Platelet Procoagulant Activity.

Knauss EA, Guci J, Luc N, Disharoon D, Huang GH, Gupta AS, Nieman MT. Knauss EA, et al. Among authors: nieman mt. bioRxiv [Preprint]. 2024 Oct 17:2024.10.14.617127. doi: 10.1101/2024.10.14.617127. bioRxiv. 2024. PMID: 39463946 Free PMC article. Preprint.

3

Prothrombin Knockdown Protects Podocytes and Reduces Proteinuria in Glomerular Disease.

Waller AP, Wolfgang KJ, Pruner I, Stevenson ZS, Abdelghani E, Muralidharan K, Wilkie TK, Blissett AR, Calomeni EP, Vetter TA, Brodsky SV, Smoyer WE, Nieman MT, Kerlin BA. Waller AP, et al. Among authors: nieman mt. bioRxiv [Preprint]. 2024 Mar 2:2023.06.20.544360. doi: 10.1101/2023.06.20.544360. bioRxiv. 2024. PMID: 38464017 Free PMC article. Preprint.

4

Protease-activated receptor 4 uses anionic residues to interact with alpha-thrombin in the absence or presence of protease-activated receptor 1.

Nieman MT. Nieman MT. Biochemistry. 2008 Dec 16;47(50):13279-86. doi: 10.1021/bi801334s. Biochemistry. 2008. PMID: 19053259

5

Mapping human protease-activated receptor 4 (PAR4) homodimer interface to transmembrane helix 4.

de la Fuente M, Noble DN, Verma S, Nieman MT. de la Fuente M, et al. Among authors: nieman mt. J Biol Chem. 2012 Mar 23;287(13):10414-10423. doi: 10.1074/jbc.M112.341438. Epub 2012 Feb 8. J Biol Chem. 2012. PMID: 22318735 Free PMC article.

6

Calcium mobilization and protein kinase C activation downstream of protease activated receptor 4 (PAR4) is negatively regulated by PAR3 in mouse platelets.

Arachiche A, de la Fuente M, Nieman MT. Arachiche A, et al. Among authors: nieman mt. PLoS One. 2013;8(2):e55740. doi: 10.1371/journal.pone.0055740. Epub 2013 Feb 6. PLoS One. 2013. PMID: 23405206 Free PMC article.

7

Protease-activated receptor 1 (PAR1) and PAR4 heterodimers are required for PAR1-enhanced cleavage of PAR4 by α-thrombin.

Arachiche A, Mumaw MM, de la Fuente M, Nieman MT. Arachiche A, et al. Among authors: nieman mt. J Biol Chem. 2013 Nov 8;288(45):32553-32562. doi: 10.1074/jbc.M113.472373. Epub 2013 Oct 4. J Biol Chem. 2013. PMID: 24097976 Free PMC article.

8

Targeting the anionic region of human protease-activated receptor 4 inhibits platelet aggregation and thrombosis without interfering with hemostasis.

Mumaw MM, de la Fuente M, Noble DN, Nieman MT. Mumaw MM, et al. Among authors: nieman mt. J Thromb Haemost. 2014 Aug;12(8):1331-41. doi: 10.1111/jth.12619. Epub 2014 Jun 27. J Thromb Haemost. 2014. PMID: 24888424 Free PMC article.

9

PARtitioning protease signaling.

Nieman MT. Nieman MT. Blood. 2015 Mar 19;125(12):1853-5. doi: 10.1182/blood-2015-01-623835. Blood. 2015. PMID: 25792732 Free article.

10

Development and characterization of monoclonal antibodies against Protease Activated Receptor 4 (PAR4).

Mumaw MM, de la Fuente M, Arachiche A, Wahl JK 3rd, Nieman MT. Mumaw MM, et al. Among authors: nieman mt. Thromb Res. 2015 Jun;135(6):1165-71. doi: 10.1016/j.thromres.2015.03.027. Epub 2015 Apr 9. Thromb Res. 2015. PMID: 25890453 Free PMC article.

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