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Screening of an FDA-approved compound library identifies four small-molecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture.
de Wilde AH, Jochmans D, Posthuma CC, Zevenhoven-Dobbe JC, van Nieuwkoop S, Bestebroer TM, van den Hoogen BG, Neyts J, Snijder EJ. de Wilde AH, et al. Among authors: jochmans d. Antimicrob Agents Chemother. 2014 Aug;58(8):4875-84. doi: 10.1128/AAC.03011-14. Epub 2014 May 19. Antimicrob Agents Chemother. 2014. PMID: 24841269 Free PMC article.
Inhibition of human immunodeficiency virus type 1 replication in human cells by Debio-025, a novel cyclophilin binding agent.
Ptak RG, Gallay PA, Jochmans D, Halestrap AP, Ruegg UT, Pallansch LA, Bobardt MD, de Béthune MP, Neyts J, De Clercq E, Dumont JM, Scalfaro P, Besseghir K, Wenger RM, Rosenwirth B. Ptak RG, et al. Among authors: jochmans d. Antimicrob Agents Chemother. 2008 Apr;52(4):1302-17. doi: 10.1128/AAC.01324-07. Epub 2008 Jan 22. Antimicrob Agents Chemother. 2008. PMID: 18212100 Free PMC article.
Favipiravir (T-705) inhibits in vitro norovirus replication.
Rocha-Pereira J, Jochmans D, Dallmeier K, Leyssen P, Nascimento MS, Neyts J. Rocha-Pereira J, et al. Among authors: jochmans d. Biochem Biophys Res Commun. 2012 Aug 10;424(4):777-80. doi: 10.1016/j.bbrc.2012.07.034. Epub 2012 Jul 15. Biochem Biophys Res Commun. 2012. PMID: 22809499
Inhibition of norovirus replication by the nucleoside analogue 2'-C-methylcytidine.
Rocha-Pereira J, Jochmans D, Dallmeier K, Leyssen P, Cunha R, Costa I, Nascimento MS, Neyts J. Rocha-Pereira J, et al. Among authors: jochmans d. Biochem Biophys Res Commun. 2012 Nov 2;427(4):796-800. doi: 10.1016/j.bbrc.2012.10.003. Epub 2012 Oct 9. Biochem Biophys Res Commun. 2012. PMID: 23063849
Intervention strategies for emerging viruses: use of antivirals.
Debing Y, Jochmans D, Neyts J. Debing Y, et al. Among authors: jochmans d. Curr Opin Virol. 2013 Apr;3(2):217-24. doi: 10.1016/j.coviro.2013.03.001. Epub 2013 Apr 4. Curr Opin Virol. 2013. PMID: 23562753 Free PMC article. Review.
Norovirus: targets and tools in antiviral drug discovery.
Rocha-Pereira J, Neyts J, Jochmans D. Rocha-Pereira J, et al. Among authors: jochmans d. Biochem Pharmacol. 2014 Sep 1;91(1):1-11. doi: 10.1016/j.bcp.2014.05.021. Epub 2014 Jun 2. Biochem Pharmacol. 2014. PMID: 24893351 Free PMC article. Review.
111 results