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Gene-lifestyle interaction and type 2 diabetes: the EPIC interact case-cohort study.
Langenberg C, Sharp SJ, Franks PW, Scott RA, Deloukas P, Forouhi NG, Froguel P, Groop LC, Hansen T, Palla L, Pedersen O, Schulze MB, Tormo MJ, Wheeler E, Agnoli C, Arriola L, Barricarte A, Boeing H, Clarke GM, Clavel-Chapelon F, Duell EJ, Fagherazzi G, Kaaks R, Kerrison ND, Key TJ, Khaw KT, Kröger J, Lajous M, Morris AP, Navarro C, Nilsson PM, Overvad K, Palli D, Panico S, Quirós JR, Rolandsson O, Sacerdote C, Sánchez MJ, Slimani N, Spijkerman AM, Tumino R, van der A DL, van der Schouw YT, Barroso I, McCarthy MI, Riboli E, Wareham NJ. Langenberg C, et al. Among authors: mccarthy mi. PLoS Med. 2014 May 20;11(5):e1001647. doi: 10.1371/journal.pmed.1001647. eCollection 2014 May. PLoS Med. 2014. PMID: 24845081 Free PMC article.
A meta-analysis of four European genome screens (GIFT Consortium) shows evidence for a novel region on chromosome 17p11.2-q22 linked to type 2 diabetes.
Demenais F, Kanninen T, Lindgren CM, Wiltshire S, Gaget S, Dandrieux C, Almgren P, Sjögren M, Hattersley A, Dina C, Tuomi T, McCarthy MI, Froguel P, Groop LC. Demenais F, et al. Among authors: mccarthy mi. Hum Mol Genet. 2003 Aug 1;12(15):1865-73. doi: 10.1093/hmg/ddg195. Hum Mol Genet. 2003. PMID: 12874106
Variation within the gene encoding the upstream stimulatory factor 1 does not influence susceptibility to type 2 diabetes in samples from populations with replicated evidence of linkage to chromosome 1q.
Zeggini E, Damcott CM, Hanson RL, Karim MA, Rayner NW, Groves CJ, Baier LJ, Hale TC, Hattersley AT, Hitman GA, Hunt SE, Knowler WC, Mitchell BD, Ng MC, O'Connell JR, Pollin TI, Vaxillaire M, Walker M, Wang X, Whittaker P, Xiang K, Jia W, Chan JC, Froguel P, Deloukas P, Shuldiner AR, Elbein SC, McCarthy MI; International Type 2 Diabetes 1q Consortium. Zeggini E, et al. Among authors: mccarthy mi. Diabetes. 2006 Sep;55(9):2541-8. doi: 10.2337/db06-0088. Diabetes. 2006. PMID: 16936202 Free article.
786 results