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Altered chromatin architecture underlies progressive impairment of the heat shock response in mouse models of Huntington disease.
Labbadia J, Cunliffe H, Weiss A, Katsyuba E, Sathasivam K, Seredenina T, Woodman B, Moussaoui S, Frentzel S, Luthi-Carter R, Paganetti P, Bates GP. Labbadia J, et al. Among authors: moussaoui s. J Clin Invest. 2011 Aug;121(8):3306-19. doi: 10.1172/JCI57413. Epub 2011 Jul 25. J Clin Invest. 2011. PMID: 21785217 Free PMC article.
Early postnatal behavioral, cellular, and molecular changes in models of Huntington disease are reversible by HDAC inhibition.
Siebzehnrübl FA, Raber KA, Urbach YK, Schulze-Krebs A, Canneva F, Moceri S, Habermeyer J, Achoui D, Gupta B, Steindler DA, Stephan M, Nguyen HP, Bonin M, Riess O, Bauer A, Aigner L, Couillard-Despres S, Paucar MA, Svenningsson P, Osmand A, Andreew A, Zabel C, Weiss A, Kuhn R, Moussaoui S, Blockx I, Van der Linden A, Cheong RY, Roybon L, Petersén Å, von Hörsten S. Siebzehnrübl FA, et al. Among authors: moussaoui s. Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):E8765-E8774. doi: 10.1073/pnas.1807962115. Epub 2018 Aug 27. Proc Natl Acad Sci U S A. 2018. PMID: 30150378 Free PMC article.
Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration.
Zwilling D, Huang SY, Sathyasaikumar KV, Notarangelo FM, Guidetti P, Wu HQ, Lee J, Truong J, Andrews-Zwilling Y, Hsieh EW, Louie JY, Wu T, Scearce-Levie K, Patrick C, Adame A, Giorgini F, Moussaoui S, Laue G, Rassoulpour A, Flik G, Huang Y, Muchowski JM, Masliah E, Schwarcz R, Muchowski PJ. Zwilling D, et al. Among authors: moussaoui s. Cell. 2011 Jun 10;145(6):863-74. doi: 10.1016/j.cell.2011.05.020. Cell. 2011. PMID: 21640374 Free PMC article.
106 results