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The multikinase inhibitor Sorafenib displays significant antiproliferative effects and induces apoptosis via caspase 3, 7 and PARP in B- and T-lymphoblastic cells.
Schult C, Dahlhaus M, Ruck S, Sawitzky M, Amoroso F, Lange S, Etro D, Glass A, Fuellen G, Boldt S, Wolkenhauer O, Neri LM, Freund M, Junghanss C. Schult C, et al. Among authors: fuellen g. BMC Cancer. 2010 Oct 15;10:560. doi: 10.1186/1471-2407-10-560. BMC Cancer. 2010. PMID: 20950443 Free PMC article.
In silico approaches and the role of ontologies in aging research.
Fuellen G, Boerries M, Busch H, de Grey A, Hahn U, Hiller T, Hoeflich A, Jansen L, Janssens GE, Kaleta C, Meinema AC, Schäuble S, Simm A, Schofield PN, Smith B, Sühnel J, Vera J, Wagner W, Wönne EC, Wuttke D. Fuellen G, et al. Rejuvenation Res. 2013 Dec;16(6):540-6. doi: 10.1089/rej.2013.1517. Rejuvenation Res. 2013. PMID: 24188080 Free PMC article.
Systems biology approaches in aging research.
Chauhan A, Liebal UW, Vera J, Baltrusch S, Junghanß C, Tiedge M, Fuellen G, Wolkenhauer O, Köhling R. Chauhan A, et al. Among authors: fuellen g. Interdiscip Top Gerontol. 2015;40:155-76. doi: 10.1159/000364981. Epub 2014 Oct 14. Interdiscip Top Gerontol. 2015. PMID: 25341520 Free article. Review.
A mutation in the NADH-dehydrogenase subunit 2 suppresses fibroblast aging.
Schauer M, Kottek T, Schönherr M, Bhattacharya A, Ibrahim SM, Hirose M, Köhling R, Fuellen G, Schmitz U, Kunz M. Schauer M, et al. Among authors: fuellen g. Oncotarget. 2015 Apr 20;6(11):8552-66. doi: 10.18632/oncotarget.3298. Oncotarget. 2015. PMID: 25839158 Free PMC article.
Advanced Running Performance by Genetic Predisposition in Male Dummerstorf Marathon Mice (DUhTP) Reveals Higher Sterol Regulatory Element-Binding Protein (SREBP) Related mRNA Expression in the Liver and Higher Serum Levels of Progesterone.
Ohde D, Moeller M, Brenmoehl J, Walz C, Ponsuksili S, Schwerin M, Fuellen G, Hoeflich A. Ohde D, et al. Among authors: fuellen g. PLoS One. 2016 Jan 22;11(1):e0146748. doi: 10.1371/journal.pone.0146748. eCollection 2016. PLoS One. 2016. PMID: 26799318 Free PMC article.
135 results