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Combination of the PI3K inhibitor Idelalisib with the conventional cytostatics cytarabine and dexamethasone leads to changes in pathway activation that induce anti-proliferative effects in B lymphoblastic leukaemia cell lines.
Sklarz LM, Gladbach YS, Ernst M, Hamed M, Roolf C, Sender S, Beck J, Schütz E, Fischer S, Struckmann S, Junghanss C, Fuellen G, Murua Escobar H. Sklarz LM, et al. Among authors: roolf c. Cancer Cell Int. 2020 Aug 12;20:390. doi: 10.1186/s12935-020-01431-4. eCollection 2020. Cancer Cell Int. 2020. PMID: 32817744 Free PMC article.
Comparative High-Resolution Transcriptome Sequencing of Lymphoma Cell Lines and de novo Lymphomas Reveals Cell-Line-Specific Pathway Dysregulation.
Taher L, Beck J, Liu W, Roolf C, Soller JT, Rütgen BC, Hammer SE, Chodisetti M, Sender S, Sterenczak KA, Fuellen G, Junghanss C, Brenig B, Nolte I, Schütz E, Murua Escobar H. Taher L, et al. Among authors: roolf c. Sci Rep. 2018 Apr 19;8(1):6279. doi: 10.1038/s41598-018-23207-7. Sci Rep. 2018. PMID: 29674676 Free PMC article.
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