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Systems biologists seek fuller integration of systems biology approaches in new cancer research programs.
Wolkenhauer O, Auffray C, Baltrusch S, Blüthgen N, Byrne H, Cascante M, Ciliberto A, Dale T, Drasdo D, Fell D, Ferrell JE Jr, Gallahan D, Gatenby R, Günther U, Harms BD, Herzel H, Junghanss C, Kunz M, van Leeuwen I, Lenormand P, Levi F, Linnebacher M, Lowengrub J, Maini PK, Malik A, Rateitschak K, Sansom O, Schäfer R, Schürrle K, Sers C, Schnell S, Shibata D, Tyson J, Vera J, White M, Zhivotovsky B, Jaster R. Wolkenhauer O, et al. Cancer Res. 2010 Jan 1;70(1):12-3. doi: 10.1158/0008-5472.CAN-09-2676. Epub 2009 Dec 22. Cancer Res. 2010. PMID: 20028868 Free PMC article.
The multikinase inhibitor Sorafenib displays significant antiproliferative effects and induces apoptosis via caspase 3, 7 and PARP in B- and T-lymphoblastic cells.
Schult C, Dahlhaus M, Ruck S, Sawitzky M, Amoroso F, Lange S, Etro D, Glass A, Fuellen G, Boldt S, Wolkenhauer O, Neri LM, Freund M, Junghanss C. Schult C, et al. Among authors: wolkenhauer o. BMC Cancer. 2010 Oct 15;10:560. doi: 10.1186/1471-2407-10-560. BMC Cancer. 2010. PMID: 20950443 Free PMC article.
Systems biology of JAK-STAT signalling in human malignancies.
Vera J, Rateitschak K, Lange F, Kossow C, Wolkenhauer O, Jaster R. Vera J, et al. Among authors: wolkenhauer o. Prog Biophys Mol Biol. 2011 Aug;106(2):426-34. doi: 10.1016/j.pbiomolbio.2011.06.013. Epub 2011 Jul 6. Prog Biophys Mol Biol. 2011. PMID: 21762720 Review.
237 results