Mellert HS - Search Results

1

Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms.

Allen MA, Andrysik Z, Dengler VL, Mellert HS, Guarnieri A, Freeman JA, Sullivan KD, Galbraith MD, Luo X, Kraus WL, Dowell RD, Espinosa JM. Allen MA, et al. Among authors: mellert hs. Elife. 2014 May 27;3:e02200. doi: 10.7554/eLife.02200. Elife. 2014. PMID: 24867637 Free PMC article.

2

Tumor suppression by p53: is apoptosis important or not?

Mellert H, Espinosa JM. Mellert H, et al. Cell Rep. 2013 May 30;3(5):1335-6. doi: 10.1016/j.celrep.2013.05.011. Cell Rep. 2013. PMID: 23726020 Free article.

3

A rare DNA contact mutation in cancer confers p53 gain-of-function and tumor cell survival via TNFAIP8 induction.

Monteith JA, Mellert H, Sammons MA, Kuswanto LA, Sykes SM, Resnick-Silverman L, Manfredi JJ, Berger SL, McMahon SB. Monteith JA, et al. Mol Oncol. 2016 Oct;10(8):1207-20. doi: 10.1016/j.molonc.2016.05.007. Epub 2016 Jun 7. Mol Oncol. 2016. PMID: 27341992 Free PMC article.

4

The retinoblastoma tumor suppressor modulates DNA repair and radioresponsiveness.

Thangavel C, Boopathi E, Ciment S, Liu Y, O'Neill R, Sharma A, McMahon SB, Mellert H, Addya S, Ertel A, Birbe R, Fortina P, Dicker AP, Knudsen KE, Den RB. Thangavel C, et al. Clin Cancer Res. 2014 Nov 1;20(21):5468-5482. doi: 10.1158/1078-0432.CCR-14-0326. Epub 2014 Aug 27. Clin Cancer Res. 2014. PMID: 25165096 Free PMC article.

5

Multi-focal control of mitochondrial gene expression by oncogenic MYC provides potential therapeutic targets in cancer.

Oran AR, Adams CM, Zhang XY, Gennaro VJ, Pfeiffer HK, Mellert HS, Seidel HE, Mascioli K, Kaplan J, Gaballa MR, Shen C, Rigoutsos I, King MP, Cotney JL, Arnold JJ, Sharma SD, Martinez-Outschoorn UE, Vakoc CR, Chodosh LA, Thompson JE, Bradner JE, Cameron CE, Shadel GS, Eischen CM, McMahon SB. Oran AR, et al. Among authors: mellert hs. Oncotarget. 2016 Nov 8;7(45):72395-72414. doi: 10.18632/oncotarget.11718. Oncotarget. 2016. PMID: 27590350 Free PMC article.

6

Myc overexpression brings out unexpected antiapoptotic effects of miR-34a.

Sotillo E, Laver T, Mellert H, Schelter JM, Cleary MA, McMahon S, Thomas-Tikhonenko A. Sotillo E, et al. Oncogene. 2011 Jun 2;30(22):2587-94. doi: 10.1038/onc.2010.634. Epub 2011 Feb 7. Oncogene. 2011. PMID: 21297663 Free PMC article.

7

Phosphorylation of Tip60 by GSK-3 determines the induction of PUMA and apoptosis by p53.

Charvet C, Wissler M, Brauns-Schubert P, Wang SJ, Tang Y, Sigloch FC, Mellert H, Brandenburg M, Lindner SE, Breit B, Green DR, McMahon SB, Borner C, Gu W, Maurer U. Charvet C, et al. Mol Cell. 2011 Jun 10;42(5):584-96. doi: 10.1016/j.molcel.2011.03.033. Mol Cell. 2011. PMID: 21658600 Free PMC article.

8

Deacetylation of the DNA-binding domain regulates p53-mediated apoptosis.

Mellert HS, Stanek TJ, Sykes SM, Rauscher FJ 3rd, Schultz DC, McMahon SB. Mellert HS, et al. J Biol Chem. 2011 Feb 11;286(6):4264-70. doi: 10.1074/jbc.M110.184663. Epub 2010 Dec 9. J Biol Chem. 2011. PMID: 21148320 Free PMC article.

9

Biochemical pathways that regulate acetyltransferase and deacetylase activity in mammalian cells.

Mellert HS, McMahon SB. Mellert HS, et al. Trends Biochem Sci. 2009 Nov;34(11):571-8. doi: 10.1016/j.tibs.2009.06.010. Epub 2009 Oct 12. Trends Biochem Sci. 2009. PMID: 19819149 Free PMC article. Review.

10

hMOF, a KAT(8) with many lives.

Mellert HS, McMahon SB. Mellert HS, et al. Mol Cell. 2009 Oct 23;36(2):174-5. doi: 10.1016/j.molcel.2009.10.005. Mol Cell. 2009. PMID: 19854127 Free article.

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