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Cross-species genomic and functional analyses identify a combination therapy using a CHK1 inhibitor and a ribonucleotide reductase inhibitor to treat triple-negative breast cancer.
Bennett CN, Tomlinson CC, Michalowski AM, Chu IM, Luger D, Mittereder LR, Aprelikova O, Shou J, Piwinica-Worms H, Caplen NJ, Hollingshead MG, Green JE. Bennett CN, et al. Among authors: michalowski am. Breast Cancer Res. 2012 Jul 19;14(4):R109. doi: 10.1186/bcr3230. Breast Cancer Res. 2012. PMID: 22812567 Free PMC article.
Cooperative Targets of Combined mTOR/HDAC Inhibition Promote MYC Degradation.
Simmons JK, Michalowski AM, Gamache BJ, DuBois W, Patel J, Zhang K, Gary J, Zhang S, Gaikwad S, Connors D, Watson N, Leon E, Chen JQ, Kuehl WM, Lee MP, Zingone A, Landgren O, Ordentlich P, Huang J, Mock BA. Simmons JK, et al. Among authors: michalowski am. Mol Cancer Ther. 2017 Sep;16(9):2008-2021. doi: 10.1158/1535-7163.MCT-17-0171. Epub 2017 May 18. Mol Cancer Ther. 2017. PMID: 28522584 Free PMC article.
T-Cell Deletion of MyD88 Connects IL17 and IκBζ to RAS Oncogenesis.
Cataisson C, Salcedo R, Michalowski AM, Klosterman M, Naik S, Li L, Pan MJ, Sweet A, Chen JQ, Kostecka LG, Karwan M, Smith L, Dai RM, Stewart CA, Lyakh L, Hsieh WT, Khan A, Yang H, Lee M, Trinchieri G, Yuspa SH. Cataisson C, et al. Among authors: michalowski am. Mol Cancer Res. 2019 Aug;17(8):1759-1773. doi: 10.1158/1541-7786.MCR-19-0227. Epub 2019 Jun 4. Mol Cancer Res. 2019. PMID: 31164412 Free PMC article.
Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis.
Marie KL, Sassano A, Yang HH, Michalowski AM, Michael HT, Guo T, Tsai YC, Weissman AM, Lee MP, Jenkins LM, Zaidi MR, Pérez-Guijarro E, Day CP, Ylaya K, Hewitt SM, Patel NL, Arnheiter H, Davis S, Meltzer PS, Merlino G, Mishra PJ. Marie KL, et al. Among authors: michalowski am. Nat Commun. 2020 Jan 16;11(1):333. doi: 10.1038/s41467-019-14085-2. Nat Commun. 2020. PMID: 31949145 Free PMC article.
Multimodel preclinical platform predicts clinical response of melanoma to immunotherapy.
Pérez-Guijarro E, Yang HH, Araya RE, El Meskini R, Michael HT, Vodnala SK, Marie KL, Smith C, Chin S, Lam KC, Thorkelsson A, Iacovelli AJ, Kulaga A, Fon A, Michalowski AM, Hugo W, Lo RS, Restifo NP, Sharan SK, Van Dyke T, Goldszmid RS, Weaver Ohler Z, Lee MP, Day CP, Merlino G. Pérez-Guijarro E, et al. Among authors: michalowski am. Nat Med. 2020 May;26(5):781-791. doi: 10.1038/s41591-020-0818-3. Epub 2020 Apr 13. Nat Med. 2020. PMID: 32284588 Free PMC article.
Author Correction: Multimodel preclinical platform predicts clinical response of melanoma to immunotherapy.
Pérez-Guijarro E, Yang HH, Araya RE, El Meskini R, Michael HT, Vodnala SK, Marie KL, Smith C, Chin S, Lam KC, Thorkelsson A, Iacovelli AJ, Kulaga A, Fon A, Michalowski AM, Hugo W, Lo RS, Restifo NP, Sharan SK, Van Dyke T, Goldszmid RS, Weaver Ohler Z, Lee MP, Day CP, Merlino G. Pérez-Guijarro E, et al. Among authors: michalowski am. Nat Med. 2021 Feb;27(2):355. doi: 10.1038/s41591-021-01252-6. Nat Med. 2021. PMID: 33514948 No abstract available.
32 results