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The metabolism and disposition of GSK2140944 in healthy human subjects.
Negash K, Andonian C, Felgate C, Chen C, Goljer I, Squillaci B, Nguyen D, Pirhalla J, Lev M, Schubert E, Tiffany C, Hossain M, Ho M. Negash K, et al. Among authors: hossain m. Xenobiotica. 2016 Aug;46(8):683-702. doi: 10.3109/00498254.2015.1112933. Epub 2015 Nov 19. Xenobiotica. 2016. PMID: 26586303
A Phase I, Randomized, Double-Blinded, Placebo- and Moxifloxacin-Controlled, Four-Period Crossover Study To Evaluate the Effect of Gepotidacin on Cardiac Conduction as Assessed by 12-Lead Electrocardiogram in Healthy Volunteers.
Hossain M, Zhou M, Tiffany C, Dumont E, Darpo B. Hossain M, et al. Antimicrob Agents Chemother. 2017 Apr 24;61(5):e02385-16. doi: 10.1128/AAC.02385-16. Print 2017 May. Antimicrob Agents Chemother. 2017. PMID: 28223381 Free PMC article. Clinical Trial.
Pharmacokinetics of Oral Formulations of Gepotidacin (GSK2140944), a Triazaacenaphthylene Bacterial Type II Topoisomerase Inhibitor, in Healthy Adult and Adolescent Participants.
Barth A, Hossain M, Brimhall DB, Perry CR, Tiffany CA, Xu S, Dumont EF. Barth A, et al. Among authors: hossain m. Antimicrob Agents Chemother. 2022 Jan 18;66(1):e0126321. doi: 10.1128/AAC.01263-21. Epub 2021 Oct 11. Antimicrob Agents Chemother. 2022. PMID: 34633853 Free PMC article. Clinical Trial.
Efficacy, Safety, and Tolerability of Gepotidacin (GSK2140944) in the Treatment of Patients with Suspected or Confirmed Gram-Positive Acute Bacterial Skin and Skin Structure Infections.
O'Riordan W, Tiffany C, Scangarella-Oman N, Perry C, Hossain M, Ashton T, Dumont E. O'Riordan W, et al. Among authors: hossain m. Antimicrob Agents Chemother. 2017 May 24;61(6):e02095-16. doi: 10.1128/AAC.02095-16. Print 2017 Jun. Antimicrob Agents Chemother. 2017. PMID: 28373199 Free PMC article. Clinical Trial.
Pharmacokinetics of Gepotidacin in Renal Impairment.
Hossain M, Tiffany C, Raychaudhuri A, Nguyen D, Tai G, Alcorn H Jr, Preston RA, Marbury T, Dumont E. Hossain M, et al. Clin Pharmacol Drug Dev. 2020 Jul;9(5):560-572. doi: 10.1002/cpdd.807. Epub 2020 May 19. Clin Pharmacol Drug Dev. 2020. PMID: 32429000 Free PMC article. Clinical Trial.
7,486 results