Fishwick CW - Search Results

1

Structure guided development of potent reversibly binding penicillin binding protein inhibitors.

Woon EC, Zervosen A, Sauvage E, Simmons KJ, Zivec M, Inglis SR, Fishwick CW, Gobec S, Charlier P, Luxen A, Schofield CJ. Woon EC, et al. Among authors: fishwick cw. ACS Med Chem Lett. 2011 Jan 11;2(3):219-23. doi: 10.1021/ml100260x. eCollection 2011 Mar 10. ACS Med Chem Lett. 2011. PMID: 24900305 Free PMC article.

2

From TgO/GABA-AT, GABA, and T-263 Mutant to Conception of Toxoplasma.

Lykins J, Moschitto MJ, Zhou Y, Filippova EV, Le HV, Tomita T, Fox BA, Bzik DJ, Su C, Rajagopala SV, Flores K, Spano F, Woods S, Roberts CW, Hua C, El Bissati K, Wheeler KM, Dovgin S, Muench SP, McPhillie M, Fishwick CWG, Anderson WF, Lee PJ, Hickman M, Weiss LM, Dubey JP, Lorenzi HA, Silverman RB, McLeod RL. Lykins J, et al. Among authors: fishwick cwg. iScience. 2023 Nov 16;27(1):108477. doi: 10.1016/j.isci.2023.108477. eCollection 2024 Jan 19. iScience. 2023. PMID: 38205261 Free PMC article.

3

Design and synthesis of potent inhibitors of the malaria parasite dihydroorotate dehydrogenase.

Heikkilä T, Ramsey C, Davies M, Galtier C, Stead AM, Johnson AP, Fishwick CW, Boa AN, McConkey GA. Heikkilä T, et al. Among authors: fishwick cw. J Med Chem. 2007 Jan 25;50(2):186-91. doi: 10.1021/jm060687j. J Med Chem. 2007. PMID: 17228860

4

Derivatives of pyrimidine, phthalimide and anthranilic acid as inhibitors of human hydroxysteroid dehydrogenase AKR1C1.

Brozic P, Cesar J, Kovac A, Davies M, Johnson AP, Fishwick CW, Lanisnik Rizner T, Gobec S. Brozic P, et al. Among authors: fishwick cw. Chem Biol Interact. 2009 Mar 16;178(1-3):158-64. doi: 10.1016/j.cbi.2008.10.019. Epub 2008 Oct 22. Chem Biol Interact. 2009. PMID: 19007763

5

Design and synthesis of new hydroxyethylamines as inhibitors of D-alanyl-D-lactate ligase (VanA) and D-alanyl-D-alanine ligase (DdlB).

Sova M, Cadez G, Turk S, Majce V, Polanc S, Batson S, Lloyd AJ, Roper DI, Fishwick CW, Gobec S. Sova M, et al. Among authors: fishwick cw. Bioorg Med Chem Lett. 2009 Mar 1;19(5):1376-9. doi: 10.1016/j.bmcl.2009.01.034. Epub 2009 Jan 19. Bioorg Med Chem Lett. 2009. PMID: 19196510

6

The nature of Staphylococcus aureus MurA and MurZ and approaches for detection of peptidoglycan biosynthesis inhibitors.

Blake KL, O'Neill AJ, Mengin-Lecreulx D, Henderson PJ, Bostock JM, Dunsmore CJ, Simmons KJ, Fishwick CW, Leeds JA, Chopra I. Blake KL, et al. Among authors: fishwick cw. Mol Microbiol. 2009 Apr;72(2):335-43. doi: 10.1111/j.1365-2958.2009.06648.x. Epub 2009 Mar 3. Mol Microbiol. 2009. PMID: 19298367 Free article.

7

Structure-based design, synthesis, and characterization of inhibitors of human and Plasmodium falciparum dihydroorotate dehydrogenases.

Davies M, Heikkilä T, McConkey GA, Fishwick CW, Parsons MR, Johnson AP. Davies M, et al. Among authors: fishwick cw. J Med Chem. 2009 May 14;52(9):2683-93. doi: 10.1021/jm800963t. J Med Chem. 2009. PMID: 19351152

8

Discovery of novel non-peptide inhibitors of BACE-1 using virtual high-throughput screening.

Yi Mok N, Chadwick J, Kellett KA, Hooper NM, Johnson AP, Fishwick CW. Yi Mok N, et al. Among authors: fishwick cw. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6770-4. doi: 10.1016/j.bmcl.2009.09.103. Epub 2009 Oct 2. Bioorg Med Chem Lett. 2009. PMID: 19854048

9

A study of the effects of substituents on the selectivity of the binding of N-arylaminomethylene malonate inhibitors to DHODH.

Cowen D, Bedingfield P, McConkey GA, Fishwick CW, Johnson AP. Cowen D, et al. Among authors: fishwick cw. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1284-7. doi: 10.1016/j.bmcl.2009.11.079. Epub 2009 Nov 27. Bioorg Med Chem Lett. 2010. PMID: 20034791

10

Structure-based discovery of antibacterial drugs.

Simmons KJ, Chopra I, Fishwick CW. Simmons KJ, et al. Among authors: fishwick cw. Nat Rev Microbiol. 2010 Jul;8(7):501-10. doi: 10.1038/nrmicro2349. Nat Rev Microbiol. 2010. PMID: 20551974 Review.

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