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SorCS2 regulates dopaminergic wiring and is processed into an apoptotic two-chain receptor in peripheral glia.
Glerup S, Olsen D, Vaegter CB, Gustafsen C, Sjoegaard SS, Hermey G, Kjolby M, Molgaard S, Ulrichsen M, Boggild S, Skeldal S, Fjorback AN, Nyengaard JR, Jacobsen J, Bender D, Bjarkam CR, Sørensen ES, Füchtbauer EM, Eichele G, Madsen P, Willnow TE, Petersen CM, Nykjaer A. Glerup S, et al. Among authors: hermey g. Neuron. 2014 Jun 4;82(5):1074-87. doi: 10.1016/j.neuron.2014.04.022. Neuron. 2014. PMID: 24908487 Free article.
The mosaic receptor sorLA/LR11 binds components of the plasminogen-activating system and platelet-derived growth factor-BB similarly to LRP1 (low-density lipoprotein receptor-related protein), but mediates slow internalization of bound ligand.
Gliemann J, Hermey G, Nykjaer A, Petersen CM, Jacobsen C, Andreasen PA. Gliemann J, et al. Among authors: hermey g. Biochem J. 2004 Jul 1;381(Pt 1):203-12. doi: 10.1042/BJ20040149. Biochem J. 2004. PMID: 15053742 Free PMC article.
Functional organization of the sortilin Vps10p domain.
Westergaard UB, Sørensen ES, Hermey G, Nielsen MS, Nykjaer A, Kirkegaard K, Jacobsen C, Gliemann J, Madsen P, Petersen CM. Westergaard UB, et al. Among authors: hermey g. J Biol Chem. 2004 Nov 26;279(48):50221-9. doi: 10.1074/jbc.M408873200. Epub 2004 Sep 10. J Biol Chem. 2004. PMID: 15364913 Free article.
Different motifs regulate trafficking of SorCS1 isoforms.
Nielsen MS, Keat SJ, Hamati JW, Madsen P, Gutzmann JJ, Engelsberg A, Pedersen KM, Gustafsen C, Nykjaer A, Gliemann J, Hermans-Borgmeyer I, Kuhl D, Petersen CM, Hermey G. Nielsen MS, et al. Among authors: hermey g. Traffic. 2008 Jun;9(6):980-94. doi: 10.1111/j.1600-0854.2008.00731.x. Epub 2008 Feb 27. Traffic. 2008. PMID: 18315530 Free article.
Human sorCS1 binds sortilin and hampers its cellular functions.
Larsen JV, Hermey G, Sørensen ES, Prabakaran T, Christensen EI, Gliemann J, Madsen P, Petersen CM. Larsen JV, et al. Among authors: hermey g. Biochem J. 2014 Jan 15;457(2):277-88. doi: 10.1042/BJ20130386. Biochem J. 2014. PMID: 24128306
SORCS1 and SORCS3 control energy balance and orexigenic peptide production.
Subkhangulova A, Malik AR, Hermey G, Popp O, Dittmar G, Rathjen T, Poy MN, Stumpf A, Beed PS, Schmitz D, Breiderhoff T, Willnow TE. Subkhangulova A, et al. Among authors: hermey g. EMBO Rep. 2018 Apr;19(4):e44810. doi: 10.15252/embr.201744810. Epub 2018 Feb 12. EMBO Rep. 2018. PMID: 29440124 Free PMC article.
40 results