Burridge K - Search Results

1

Haemodynamic and extracellular matrix cues regulate the mechanical phenotype and stiffness of aortic endothelial cells.

Collins C, Osborne LD, Guilluy C, Chen Z, O'Brien ET 3rd, Reader JS, Burridge K, Superfine R, Tzima E. Collins C, et al. Among authors: burridge k. Nat Commun. 2014 Jun 11;5:3984. doi: 10.1038/ncomms4984. Nat Commun. 2014. PMID: 24917553 Free PMC article.

2

From mechanical force to RhoA activation.

Lessey EC, Guilluy C, Burridge K. Lessey EC, et al. Among authors: burridge k. Biochemistry. 2012 Sep 25;51(38):7420-32. doi: 10.1021/bi300758e. Epub 2012 Sep 10. Biochemistry. 2012. PMID: 22931484 Free PMC article. Review.

3

Localized tensional forces on PECAM-1 elicit a global mechanotransduction response via the integrin-RhoA pathway.

Collins C, Guilluy C, Welch C, O'Brien ET, Hahn K, Superfine R, Burridge K, Tzima E. Collins C, et al. Among authors: burridge k. Curr Biol. 2012 Nov 20;22(22):2087-94. doi: 10.1016/j.cub.2012.08.051. Epub 2012 Oct 18. Curr Biol. 2012. PMID: 23084990 Free PMC article.

4

Isolated nuclei adapt to force and reveal a mechanotransduction pathway in the nucleus.

Guilluy C, Osborne LD, Van Landeghem L, Sharek L, Superfine R, Garcia-Mata R, Burridge K. Guilluy C, et al. Among authors: burridge k. Nat Cell Biol. 2014 Apr;16(4):376-81. doi: 10.1038/ncb2927. Epub 2014 Mar 9. Nat Cell Biol. 2014. PMID: 24609268 Free PMC article.

5

Focal adhesions, stress fibers and mechanical tension.

Burridge K, Guilluy C. Burridge K, et al. Exp Cell Res. 2016 Apr 10;343(1):14-20. doi: 10.1016/j.yexcr.2015.10.029. Epub 2015 Oct 28. Exp Cell Res. 2016. PMID: 26519907 Free PMC article. Review.

6

The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins.

Guilluy C, Swaminathan V, Garcia-Mata R, O'Brien ET, Superfine R, Burridge K. Guilluy C, et al. Among authors: burridge k. Nat Cell Biol. 2011 Jun;13(6):722-7. doi: 10.1038/ncb2254. Epub 2011 May 15. Nat Cell Biol. 2011. PMID: 21572419 Free PMC article.

7

The vinculin C-terminal hairpin mediates F-actin bundle formation, focal adhesion, and cell mechanical properties.

Shen K, Tolbert CE, Guilluy C, Swaminathan VS, Berginski ME, Burridge K, Superfine R, Campbell SL. Shen K, et al. Among authors: burridge k. J Biol Chem. 2011 Dec 30;286(52):45103-15. doi: 10.1074/jbc.M111.244293. Epub 2011 Nov 3. J Biol Chem. 2011. PMID: 22052910 Free PMC article.

8

The RhoA guanine nucleotide exchange factor, LARG, mediates ICAM-1-dependent mechanotransduction in endothelial cells to stimulate transendothelial migration.

Lessey-Morillon EC, Osborne LD, Monaghan-Benson E, Guilluy C, O'Brien ET, Superfine R, Burridge K. Lessey-Morillon EC, et al. Among authors: burridge k. J Immunol. 2014 Apr 1;192(7):3390-8. doi: 10.4049/jimmunol.1302525. Epub 2014 Feb 28. J Immunol. 2014. PMID: 24585879 Free PMC article.

9

Phosphorylation at Y1065 in vinculin mediates actin bundling, cell spreading, and mechanical responses to force.

Tolbert CE, Thompson PM, Superfine R, Burridge K, Campbell SL. Tolbert CE, et al. Among authors: burridge k. Biochemistry. 2014 Sep 2;53(34):5526-36. doi: 10.1021/bi500678x. Epub 2014 Aug 21. Biochemistry. 2014. PMID: 25115937 Free PMC article.

10

Using magnets and magnetic beads to dissect signaling pathways activated by mechanical tension applied to cells.

Marjoram RJ, Guilluy C, Burridge K. Marjoram RJ, et al. Among authors: burridge k. Methods. 2016 Feb 1;94:19-26. doi: 10.1016/j.ymeth.2015.09.025. Epub 2015 Sep 30. Methods. 2016. PMID: 26427549 Free PMC article.

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