Calkin AC - Search Results

1

Transgenic expression of dominant-active IDOL in liver causes diet-induced hypercholesterolemia and atherosclerosis in mice.

Calkin AC, Lee SD, Kim J, Van Stijn CM, Wu XH, Lusis AJ, Hong C, Tangirala RI, Tontonoz P. Calkin AC, et al. Circ Res. 2014 Aug 1;115(4):442-9. doi: 10.1161/CIRCRESAHA.115.304440. Epub 2014 Jun 16. Circ Res. 2014. PMID: 24935961 Free PMC article.

2

Lack of the antioxidant enzyme glutathione peroxidase-1 accelerates atherosclerosis in diabetic apolipoprotein E-deficient mice.

Lewis P, Stefanovic N, Pete J, Calkin AC, Giunti S, Thallas-Bonke V, Jandeleit-Dahm KA, Allen TJ, Kola I, Cooper ME, de Haan JB. Lewis P, et al. Among authors: calkin ac. Circulation. 2007 Apr 24;115(16):2178-87. doi: 10.1161/CIRCULATIONAHA.106.664250. Epub 2007 Apr 9. Circulation. 2007. PMID: 17420349

3

Reconstituted high-density lipoprotein attenuates platelet function in individuals with type 2 diabetes mellitus by promoting cholesterol efflux.

Calkin AC, Drew BG, Ono A, Duffy SJ, Gordon MV, Schoenwaelder SM, Sviridov D, Cooper ME, Kingwell BA, Jackson SP. Calkin AC, et al. Circulation. 2009 Nov 24;120(21):2095-104. doi: 10.1161/CIRCULATIONAHA.109.870709. Epub 2009 Nov 9. Circulation. 2009. PMID: 19901191 Clinical Trial.

4

Liver x receptor signaling pathways and atherosclerosis.

Calkin AC, Tontonoz P. Calkin AC, et al. Arterioscler Thromb Vasc Biol. 2010 Aug;30(8):1513-8. doi: 10.1161/ATVBAHA.109.191197. Arterioscler Thromb Vasc Biol. 2010. PMID: 20631351 Free PMC article. Review.

5

Genome-wide association studies identify new targets in cardiovascular disease.

Calkin AC, Tontonoz P. Calkin AC, et al. Sci Transl Med. 2010 Sep 8;2(48):48ps46. doi: 10.1126/scitranslmed.3001557. Sci Transl Med. 2010. PMID: 20826839

6

The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor.

Zhang L, Fairall L, Goult BT, Calkin AC, Hong C, Millard CJ, Tontonoz P, Schwabe JW. Zhang L, et al. Among authors: calkin ac. Genes Dev. 2011 Jun 15;25(12):1262-74. doi: 10.1101/gad.2056211. Genes Dev. 2011. PMID: 21685362 Free PMC article.

7

The N342S MYLIP polymorphism is associated with high total cholesterol and increased LDL receptor degradation in humans.

Weissglas-Volkov D, Calkin AC, Tusie-Luna T, Sinsheimer JS, Zelcer N, Riba L, Tino AM, Ordoñez-Sánchez ML, Cruz-Bautista I, Aguilar-Salinas CA, Tontonoz P, Pajukanta P. Weissglas-Volkov D, et al. Among authors: calkin ac. J Clin Invest. 2011 Aug;121(8):3062-71. doi: 10.1172/JCI45504. Epub 2011 Jul 18. J Clin Invest. 2011. PMID: 21765216 Free PMC article.

8

FERM-dependent E3 ligase recognition is a conserved mechanism for targeted degradation of lipoprotein receptors.

Calkin AC, Goult BT, Zhang L, Fairall L, Hong C, Schwabe JW, Tontonoz P. Calkin AC, et al. Proc Natl Acad Sci U S A. 2011 Dec 13;108(50):20107-12. doi: 10.1073/pnas.1111589108. Epub 2011 Nov 22. Proc Natl Acad Sci U S A. 2011. PMID: 22109552 Free PMC article.

9

Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR.

Calkin AC, Tontonoz P. Calkin AC, et al. Nat Rev Mol Cell Biol. 2012 Mar 14;13(4):213-24. doi: 10.1038/nrm3312. Nat Rev Mol Cell Biol. 2012. PMID: 22414897 Free PMC article. Review.

10

Estrogen receptor (ER)α-regulated lipocalin 2 expression in adipose tissue links obesity with breast cancer progression.

Drew BG, Hamidi H, Zhou Z, Villanueva CJ, Krum SA, Calkin AC, Parks BW, Ribas V, Kalajian NY, Phun J, Daraei P, Christofk HR, Hewitt SC, Korach KS, Tontonoz P, Lusis AJ, Slamon DJ, Hurvitz SA, Hevener AL. Drew BG, et al. Among authors: calkin ac. J Biol Chem. 2015 Feb 27;290(9):5566-81. doi: 10.1074/jbc.M114.606459. Epub 2014 Dec 2. J Biol Chem. 2015. PMID: 25468909 Free PMC article.

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