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Evaluation of skeletal tissue repair, part 1: assessment of novel growth-factor-releasing hydrogels in an ex vivo chick femur defect model.
Smith EL, Kanczler JM, Gothard D, Roberts CA, Wells JA, White LJ, Qutachi O, Sawkins MJ, Peto H, Rashidi H, Rojo L, Stevens MM, El Haj AJ, Rose FR, Shakesheff KM, Oreffo RO. Smith EL, et al. Among authors: wells ja. Acta Biomater. 2014 Oct;10(10):4186-96. doi: 10.1016/j.actbio.2014.06.011. Epub 2014 Jun 14. Acta Biomater. 2014. PMID: 24937137
Evaluation of skeletal tissue repair, part 2: enhancement of skeletal tissue repair through dual-growth-factor-releasing hydrogels within an ex vivo chick femur defect model.
Smith EL, Kanczler JM, Gothard D, Roberts CA, Wells JA, White LJ, Qutachi O, Sawkins MJ, Peto H, Rashidi H, Rojo L, Stevens MM, El Haj AJ, Rose FR, Shakesheff KM, Oreffo RO. Smith EL, et al. Among authors: wells ja. Acta Biomater. 2014 Oct;10(10):4197-205. doi: 10.1016/j.actbio.2014.05.025. Epub 2014 Jun 4. Acta Biomater. 2014. PMID: 24907660
In Vivo Assessment of Bone Regeneration in Alginate/Bone ECM Hydrogels with Incorporated Skeletal Stem Cells and Single Growth Factors.
Gothard D, Smith EL, Kanczler JM, Black CR, Wells JA, Roberts CA, White LJ, Qutachi O, Peto H, Rashidi H, Rojo L, Stevens MM, El Haj AJ, Rose FR, Shakesheff KM, Oreffo RO. Gothard D, et al. Among authors: wells ja. PLoS One. 2015 Dec 16;10(12):e0145080. doi: 10.1371/journal.pone.0145080. eCollection 2015. PLoS One. 2015. PMID: 26675008 Free PMC article.
Nanovibrational Stimulation of Mesenchymal Stem Cells Induces Therapeutic Reactive Oxygen Species and Inflammation for Three-Dimensional Bone Tissue Engineering.
Orapiriyakul W, Tsimbouri MP, Childs P, Campsie P, Wells J, Fernandez-Yague MA, Burgess K, Tanner KE, Tassieri M, Meek D, Vassalli M, Biggs MJP, Salmeron-Sanchez M, Oreffo ROC, Reid S, Dalby MJ. Orapiriyakul W, et al. ACS Nano. 2020 Aug 25;14(8):10027-10044. doi: 10.1021/acsnano.0c03130. Epub 2020 Jul 23. ACS Nano. 2020. PMID: 32658450 Free PMC article.
Endothelial Cells: Co-culture Spheroids.
Kanczler JM, Wells JA, Oreffo ROC. Kanczler JM, et al. Among authors: wells ja. Methods Mol Biol. 2021;2206:47-56. doi: 10.1007/978-1-0716-0916-3_5. Methods Mol Biol. 2021. PMID: 32754810
The use of nanovibration to discover specific and potent bioactive metabolites that stimulate osteogenic differentiation in mesenchymal stem cells.
Hodgkinson T, Tsimbouri PM, Llopis-Hernandez V, Campsie P, Scurr D, Childs PG, Phillips D, Donnelly S, Wells JA, O'Brien FJ, Salmeron-Sanchez M, Burgess K, Alexander M, Vassalli M, Oreffo ROC, Reid S, France DJ, Dalby MJ. Hodgkinson T, et al. Among authors: wells ja. Sci Adv. 2021 Feb 26;7(9):eabb7921. doi: 10.1126/sciadv.abb7921. Print 2021 Feb. Sci Adv. 2021. PMID: 33637520 Free PMC article.
Materials-driven fibronectin assembly on nanoscale topography enhances mesenchymal stem cell adhesion, protecting cells from bacterial virulence factors and preventing biofilm formation.
Damiati LA, Tsimbouri MP, Hernandez VL, Jayawarna V, Ginty M, Childs P, Xiao Y, Burgess K, Wells J, Sprott MR, Meek RMD, Li P, Oreffo ROC, Nobbs A, Ramage G, Su B, Salmeron-Sanchez M, Dalby MJ. Damiati LA, et al. Biomaterials. 2022 Jan;280:121263. doi: 10.1016/j.biomaterials.2021.121263. Epub 2021 Nov 17. Biomaterials. 2022. PMID: 34810036 Free article.
522 results