Simonds S - Search Results

1

Impaired kisspeptin signaling decreases metabolism and promotes glucose intolerance and obesity.

Tolson KP, Garcia C, Yen S, Simonds S, Stefanidis A, Lawrence A, Smith JT, Kauffman AS. Tolson KP, et al. Among authors: simonds s. J Clin Invest. 2014 Jul;124(7):3075-9. doi: 10.1172/JCI71075. Epub 2014 Jun 17. J Clin Invest. 2014. PMID: 24937427 Free PMC article.

2

Repeated weight cycling in obese mice causes increased appetite and glucose intolerance.

Simonds SE, Pryor JT, Cowley MA. Simonds SE, et al. Physiol Behav. 2018 Oct 1;194:184-190. doi: 10.1016/j.physbeh.2018.05.026. Epub 2018 May 26. Physiol Behav. 2018. PMID: 29842854

3

Leptin mediates the increase in blood pressure associated with obesity.

Simonds SE, Pryor JT, Ravussin E, Greenway FL, Dileone R, Allen AM, Bassi J, Elmquist JK, Keogh JM, Henning E, Myers MG Jr, Licinio J, Brown RD, Enriori PJ, O'Rahilly S, Sternson SM, Grove KL, Spanswick DC, Farooqi IS, Cowley MA. Simonds SE, et al. Cell. 2014 Dec 4;159(6):1404-16. doi: 10.1016/j.cell.2014.10.058. Cell. 2014. PMID: 25480301 Free PMC article.

4

Hypertension in obesity: is leptin the culprit?

Simonds SE, Cowley MA. Simonds SE, et al. Trends Neurosci. 2013 Feb;36(2):121-32. doi: 10.1016/j.tins.2013.01.004. Epub 2013 Jan 17. Trends Neurosci. 2013. PMID: 23333346 Review.

5

Determining the Effects of Combined Liraglutide and Phentermine on Metabolic Parameters, Blood Pressure, and Heart Rate in Lean and Obese Male Mice.

Simonds SE, Pryor JT, Koegler FH, Buch-Rasmussen AS, Kelly LE, Grove KL, Cowley MA. Simonds SE, et al. Diabetes. 2019 Apr;68(4):683-695. doi: 10.2337/db18-1149. Epub 2019 Jan 23. Diabetes. 2019. PMID: 30674622

6

Mitochondrial uncoupling in the melanocortin system differentially regulates NPY and POMC neurons to promote weight-loss.

Michael NJ, Simonds SE, van den Top M, Cowley MA, Spanswick D. Michael NJ, et al. Mol Metab. 2017 Oct;6(10):1103-1112. doi: 10.1016/j.molmet.2017.07.002. Epub 2017 Jul 8. Mol Metab. 2017. PMID: 29031712 Free PMC article.

7

Elevated hypothalamic TCPTP in obesity contributes to cellular leptin resistance.

Loh K, Fukushima A, Zhang X, Galic S, Briggs D, Enriori PJ, Simonds S, Wiede F, Reichenbach A, Hauser C, Sims NA, Bence KK, Zhang S, Zhang ZY, Kahn BB, Neel BG, Andrews ZB, Cowley MA, Tiganis T. Loh K, et al. Among authors: simonds s. Cell Metab. 2011 Nov 2;14(5):684-99. doi: 10.1016/j.cmet.2011.09.011. Epub 2011 Oct 13. Cell Metab. 2011. PMID: 22000926 Free PMC article.

8

Food hypersensitivity-induced chronic gastrointestinal inflammation in a non-human primate model of diet-induced obesity.

Mustafa T, Li Q, Kelly LE, Gibbon A, Ryan I, Roffey K, Simonds S, Cowley MA, Sleeman MW. Mustafa T, et al. Among authors: simonds s. PLoS One. 2019 Apr 4;14(4):e0214621. doi: 10.1371/journal.pone.0214621. eCollection 2019. PLoS One. 2019. PMID: 30947272 Free PMC article.

9

Leptin action in the dorsomedial hypothalamus increases sympathetic tone to brown adipose tissue in spite of systemic leptin resistance.

Enriori PJ, Sinnayah P, Simonds SE, Garcia Rudaz C, Cowley MA. Enriori PJ, et al. J Neurosci. 2011 Aug 24;31(34):12189-97. doi: 10.1523/JNEUROSCI.2336-11.2011. J Neurosci. 2011. PMID: 21865462 Free PMC article.

10

Does leptin cause an increase in blood pressure in animals and humans?

Simonds SE, Pryor JT, Cowley MA. Simonds SE, et al. Curr Opin Nephrol Hypertens. 2017 Jan;26(1):20-25. doi: 10.1097/MNH.0000000000000287. Curr Opin Nephrol Hypertens. 2017. PMID: 27798459 Review.

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