El Sayed KA - Search Results

1

Discovery, optimization, and pharmacophore modeling of oleanolic acid and analogues as breast cancer cell migration and invasion inhibitors through targeting Brk/Paxillin/Rac1 axis.

Elsayed HE, Akl MR, Ebrahim HY, Sallam AA, Haggag EG, Kamal AM, El Sayed KA. Elsayed HE, et al. Among authors: el sayed ka. Chem Biol Drug Des. 2015 Feb;85(2):231-43. doi: 10.1111/cbdd.12380. Epub 2014 Jul 16. Chem Biol Drug Des. 2015. PMID: 24954090

2

Design and preliminary structure-activity relationship of redox-silent semisynthetic tocotrienol analogues as inhibitors for breast cancer proliferation and invasion.

Elnagar AY, Wali VB, Sylvester PW, El Sayed KA. Elnagar AY, et al. Among authors: el sayed ka. Bioorg Med Chem. 2010 Jan 15;18(2):755-68. doi: 10.1016/j.bmc.2009.11.054. Epub 2009 Nov 27. Bioorg Med Chem. 2010. PMID: 20022507

3

Design and pharmacophore modeling of biaryl methyl eugenol analogs as breast cancer invasion inhibitors.

Abdel Bar FM, Khanfar MA, Elnagar AY, Badria FA, Zaghloul AM, Ahmad KF, Sylvester PW, El Sayed KA. Abdel Bar FM, et al. Among authors: el sayed ka. Bioorg Med Chem. 2010 Jan 15;18(2):496-507. doi: 10.1016/j.bmc.2009.12.019. Epub 2009 Dec 11. Bioorg Med Chem. 2010. PMID: 20034800

4

Semisynthetic latrunculin derivatives as inhibitors of metastatic breast cancer: biological evaluations, preliminary structure-activity relationship and molecular modeling studies.

Khanfar MA, Youssef DT, El Sayed KA. Khanfar MA, et al. Among authors: el sayed ka. ChemMedChem. 2010 Feb 1;5(2):274-85. doi: 10.1002/cmdc.200900430. ChemMedChem. 2010. PMID: 20043312 Free PMC article.

5

Phenylmethylene hydantoins as prostate cancer invasion and migration inhibitors. CoMFA approach and QSAR analysis.

Khanfar MA, El Sayed KA. Khanfar MA, et al. Among authors: el sayed ka. Eur J Med Chem. 2010 Nov;45(11):5397-405. doi: 10.1016/j.ejmech.2010.08.066. Epub 2010 Sep 8. Eur J Med Chem. 2010. PMID: 20869139

6

Design, synthesis, and biological evaluation of dibromotyrosine analogues inspired by marine natural products as inhibitors of human prostate cancer proliferation, invasion, and migration.

Sallam AA, Ramasahayam S, Meyer SA, El Sayed KA. Sallam AA, et al. Among authors: el sayed ka. Bioorg Med Chem. 2010 Nov 1;18(21):7446-57. doi: 10.1016/j.bmc.2010.08.057. Epub 2010 Sep 29. Bioorg Med Chem. 2010. PMID: 20884214

7

Redox-silent tocotrienol esters as breast cancer proliferation and migration inhibitors.

Behery FA, Elnagar AY, Akl MR, Wali VB, Abuasal B, Kaddoumi A, Sylvester PW, El Sayed KA. Behery FA, et al. Among authors: el sayed ka. Bioorg Med Chem. 2010 Nov 15;18(22):8066-75. doi: 10.1016/j.bmc.2010.09.009. Epub 2010 Sep 19. Bioorg Med Chem. 2010. PMID: 20943398

8

(-)-Oleocanthal as a c-Met inhibitor for the control of metastatic breast and prostate cancers.

Elnagar AY, Sylvester PW, El Sayed KA. Elnagar AY, et al. Among authors: el sayed ka. Planta Med. 2011 Jul;77(10):1013-9. doi: 10.1055/s-0030-1270724. Epub 2011 Feb 15. Planta Med. 2011. PMID: 21328179

9

Design of semisynthetic analogues and 3D-QSAR study of eunicellin-based diterpenoids as prostate cancer migration and invasion inhibitors.

Hassan HM, Elnagar AY, Khanfar MA, Sallam AA, Mohammed R, Shaala LA, Youssef DT, Hifnawy MS, El Sayed KA. Hassan HM, et al. Among authors: el sayed ka. Eur J Med Chem. 2011 Apr;46(4):1122-30. doi: 10.1016/j.ejmech.2011.01.028. Epub 2011 Jan 28. Eur J Med Chem. 2011. PMID: 21334794

10

Semisynthetic analogues of the marine cembranoid sarcophine as prostate and breast cancer migration inhibitors.

Hassan HM, Sallam AA, Mohammed R, Hifnawy MS, Youssef DT, El Sayed KA. Hassan HM, et al. Among authors: el sayed ka. Bioorg Med Chem. 2011 Aug 15;19(16):4928-34. doi: 10.1016/j.bmc.2011.06.060. Epub 2011 Jun 28. Bioorg Med Chem. 2011. PMID: 21775154

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