Andrake M - Search Results

1

Re-purposing clinical kinase inhibitors to enhance chemosensitivity by overriding checkpoints.

Beeharry N, Banina E, Hittle J, Skobeleva N, Khazak V, Deacon S, Andrake M, Egleston BL, Peterson JR, Astsaturov I, Yen TJ. Beeharry N, et al. Among authors: andrake m. Cell Cycle. 2014;13(14):2172-91. doi: 10.4161/cc.29214. Epub 2014 Jun 23. Cell Cycle. 2014. PMID: 24955955 Free PMC article.

2

A modified HSP70 inhibitor shows broad activity as an anticancer agent.

Balaburski GM, Leu JI, Beeharry N, Hayik S, Andrake MD, Zhang G, Herlyn M, Villanueva J, Dunbrack RL Jr, Yen T, George DL, Murphy ME. Balaburski GM, et al. Among authors: andrake md. Mol Cancer Res. 2013 Mar;11(3):219-29. doi: 10.1158/1541-7786.MCR-12-0547-T. Epub 2013 Jan 9. Mol Cancer Res. 2013. PMID: 23303345 Free PMC article.

3

Genetic Variants That Predispose to DNA Double-Strand Breaks in Lymphocytes From a Subset of Patients With Familial Colorectal Carcinomas.

Arora S, Yan H, Cho I, Fan HY, Luo B, Gai X, Bodian DL, Vockley JG, Zhou Y, Handorf EA, Egleston BL, Andrake MD, Nicolas E, Serebriiskii IG, Yen TJ, Hall MJ, Golemis EA, Enders GH. Arora S, et al. Gastroenterology. 2015 Dec;149(7):1872-1883.e9. doi: 10.1053/j.gastro.2015.08.052. Epub 2015 Sep 5. Gastroenterology. 2015. PMID: 26344056 Free PMC article.

4

Systematic evaluation of underlying defects in DNA repair as an approach to case-only assessment of familial prostate cancer.

Nicolas E, Arora S, Zhou Y, Serebriiskii IG, Andrake MD, Handorf ED, Bodian DL, Vockley JG, Dunbrack RL, Ross EA, Egleston BL, Hall MJ, Golemis EA, Giri VN, Daly MB. Nicolas E, et al. Oncotarget. 2015 Nov 24;6(37):39614-33. doi: 10.18632/oncotarget.5554. Oncotarget. 2015. PMID: 26485759 Free PMC article.

5

A bifunctional regulatory element in human somatic Wee1 mediates cyclin A/Cdk2 binding and Crm1-dependent nuclear export.

Li C, Andrake M, Dunbrack R, Enders GH. Li C, et al. Among authors: andrake m. Mol Cell Biol. 2010 Jan;30(1):116-30. doi: 10.1128/MCB.01876-08. Mol Cell Biol. 2010. PMID: 19858290 Free PMC article.

6

Defects in DNA Repair Genes Predict Response to Neoadjuvant Cisplatin-based Chemotherapy in Muscle-invasive Bladder Cancer.

Plimack ER, Dunbrack RL, Brennan TA, Andrake MD, Zhou Y, Serebriiskii IG, Slifker M, Alpaugh K, Dulaimi E, Palma N, Hoffman-Censits J, Bilusic M, Wong YN, Kutikov A, Viterbo R, Greenberg RE, Chen DY, Lallas CD, Trabulsi EJ, Yelensky R, McConkey DJ, Miller VA, Golemis EA, Ross EA. Plimack ER, et al. Among authors: andrake md. Eur Urol. 2015 Dec;68(6):959-67. doi: 10.1016/j.eururo.2015.07.009. Epub 2015 Aug 1. Eur Urol. 2015. PMID: 26238431 Free PMC article.

7

Interferon-induced RIP1/RIP3-mediated necrosis requires PKR and is licensed by FADD and caspases.

Thapa RJ, Nogusa S, Chen P, Maki JL, Lerro A, Andrake M, Rall GF, Degterev A, Balachandran S. Thapa RJ, et al. Among authors: andrake m. Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):E3109-18. doi: 10.1073/pnas.1301218110. Epub 2013 Jul 29. Proc Natl Acad Sci U S A. 2013. PMID: 23898178 Free PMC article.

8

Kinase-mediated changes in nucleosome conformation trigger chromatin decondensation via poly(ADP-ribosyl)ation.

Thomas CJ, Kotova E, Andrake M, Adolf-Bryfogle J, Glaser R, Regnard C, Tulin AV. Thomas CJ, et al. Among authors: andrake m. Mol Cell. 2014 Mar 6;53(5):831-42. doi: 10.1016/j.molcel.2014.01.005. Epub 2014 Feb 6. Mol Cell. 2014. PMID: 24508391 Free PMC article.

9

BioAssemblyModeler (BAM): user-friendly homology modeling of protein homo- and heterooligomers.

Shapovalov MV, Wang Q, Xu Q, Andrake M, Dunbrack RL Jr. Shapovalov MV, et al. Among authors: andrake m. PLoS One. 2014 Jun 12;9(6):e98309. doi: 10.1371/journal.pone.0098309. eCollection 2014. PLoS One. 2014. PMID: 24922057 Free PMC article.

10

Small-Molecule Disruption of RAD52 Rings as a Mechanism for Precision Medicine in BRCA-Deficient Cancers.

Chandramouly G, McDevitt S, Sullivan K, Kent T, Luz A, Glickman JF, Andrake M, Skorski T, Pomerantz RT. Chandramouly G, et al. Among authors: andrake m. Chem Biol. 2015 Nov 19;22(11):1491-1504. doi: 10.1016/j.chembiol.2015.10.003. Epub 2015 Nov 5. Chem Biol. 2015. PMID: 26548611 Free PMC article.

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