Yen TJ - Search Results

1

Re-purposing clinical kinase inhibitors to enhance chemosensitivity by overriding checkpoints.

Beeharry N, Banina E, Hittle J, Skobeleva N, Khazak V, Deacon S, Andrake M, Egleston BL, Peterson JR, Astsaturov I, Yen TJ. Beeharry N, et al. Among authors: yen tj. Cell Cycle. 2014;13(14):2172-91. doi: 10.4161/cc.29214. Epub 2014 Jun 23. Cell Cycle. 2014. PMID: 24955955 Free PMC article.

2

Centromere fragmentation is a common mitotic defect of S and G2 checkpoint override.

Beeharry N, Rattner JB, Caviston JP, Yen T. Beeharry N, et al. Cell Cycle. 2013 May 15;12(10):1588-97. doi: 10.4161/cc.24740. Epub 2013 Apr 24. Cell Cycle. 2013. PMID: 23624842 Free PMC article.

3

Pixantrone induces cell death through mitotic perturbations and subsequent aberrant cell divisions.

Beeharry N, Di Rora AG, Smith MR, Yen TJ. Beeharry N, et al. Among authors: yen tj. Cancer Biol Ther. 2015;16(9):1397-406. doi: 10.1080/15384047.2015.1070979. Cancer Biol Ther. 2015. PMID: 26177126 Free PMC article.

4

Dose dependent effects on cell cycle checkpoints and DNA repair by bendamustine.

Beeharry N, Rattner JB, Bellacosa A, Smith MR, Yen TJ. Beeharry N, et al. Among authors: yen tj. PLoS One. 2012;7(6):e40342. doi: 10.1371/journal.pone.0040342. Epub 2012 Jun 29. PLoS One. 2012. PMID: 22768280 Free PMC article.

5

p53-dependent apoptosis in response to spindle damage is linked to loss of Bub1.

Beeharry N, Yen TJ. Beeharry N, et al. Among authors: yen tj. Cancer Biol Ther. 2009 Apr;8(7):645-7. doi: 10.4161/cbt.8.7.8140. Epub 2009 Apr 11. Cancer Biol Ther. 2009. PMID: 19270499 Free article. No abstract available.

6

Targeting WEE1 to enhance conventional therapies for acute lymphoblastic leukemia.

Ghelli Luserna Di Rorà A, Beeharry N, Imbrogno E, Ferrari A, Robustelli V, Righi S, Sabattini E, Verga Falzacappa MV, Ronchini C, Testoni N, Baldazzi C, Papayannidis C, Abbenante MC, Marconi G, Paolini S, Parisi S, Sartor C, Fontana MC, De Matteis S, Iacobucci I, Pelicci PG, Cavo M, Yen TJ, Martinelli G. Ghelli Luserna Di Rorà A, et al. Among authors: yen tj. J Hematol Oncol. 2018 Aug 1;11(1):99. doi: 10.1186/s13045-018-0641-1. J Hematol Oncol. 2018. PMID: 30068368 Free PMC article.

7

Phosphorylation sites in BubR1 that regulate kinetochore attachment, tension, and mitotic exit.

Huang H, Hittle J, Zappacosta F, Annan RS, Hershko A, Yen TJ. Huang H, et al. Among authors: yen tj. J Cell Biol. 2008 Nov 17;183(4):667-80. doi: 10.1083/jcb.200805163. J Cell Biol. 2008. PMID: 19015317 Free PMC article.

8

HuR posttranscriptionally regulates WEE1: implications for the DNA damage response in pancreatic cancer cells.

Lal S, Burkhart RA, Beeharry N, Bhattacharjee V, Londin ER, Cozzitorto JA, Romeo C, Jimbo M, Norris ZA, Yeo CJ, Sawicki JA, Winter JM, Rigoutsos I, Yen TJ, Brody JR. Lal S, et al. Among authors: yen tj. Cancer Res. 2014 Feb 15;74(4):1128-40. doi: 10.1158/0008-5472.CAN-13-1915. Cancer Res. 2014. PMID: 24536047 Free PMC article.

9

Characterization of ATM expression, localization, and associated DNA-dependent protein kinase activity.

Gately DP, Hittle JC, Chan GK, Yen TJ. Gately DP, et al. Among authors: yen tj. Mol Biol Cell. 1998 Sep;9(9):2361-74. doi: 10.1091/mbc.9.9.2361. Mol Biol Cell. 1998. PMID: 9725899 Free PMC article.

10

Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC.

Chan GK, Jablonski SA, Sudakin V, Hittle JC, Yen TJ. Chan GK, et al. Among authors: yen tj. J Cell Biol. 1999 Sep 6;146(5):941-54. doi: 10.1083/jcb.146.5.941. J Cell Biol. 1999. PMID: 10477750 Free PMC article.

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