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Seaweed natural products modify the host inflammatory response via Nrf2 signaling and alter colon microbiota composition and gene expression.
Bousquet MS, Ratnayake R, Pope JL, Chen QY, Zhu F, Chen S, Carney TJ, Gharaibeh RZ, Jobin C, Paul VJ, Luesch H. Bousquet MS, et al. Among authors: pope jl. Free Radic Biol Med. 2020 Jan;146:306-323. doi: 10.1016/j.freeradbiomed.2019.09.013. Epub 2019 Sep 16. Free Radic Biol Med. 2020. PMID: 31536771 Free PMC article.
Human colon mucosal biofilms from healthy or colon cancer hosts are carcinogenic.
Tomkovich S, Dejea CM, Winglee K, Drewes JL, Chung L, Housseau F, Pope JL, Gauthier J, Sun X, Mühlbauer M, Liu X, Fathi P, Anders RA, Besharati S, Perez-Chanona E, Yang Y, Ding H, Wu X, Wu S, White JR, Gharaibeh RZ, Fodor AA, Wang H, Pardoll DM, Jobin C, Sears CL. Tomkovich S, et al. Among authors: pope jl. J Clin Invest. 2019 Mar 11;129(4):1699-1712. doi: 10.1172/JCI124196. eCollection 2019 Mar 11. J Clin Invest. 2019. PMID: 30855275 Free PMC article.
Intestinal microbiota enhances pancreatic carcinogenesis in preclinical models.
Thomas RM, Gharaibeh RZ, Gauthier J, Beveridge M, Pope JL, Guijarro MV, Yu Q, He Z, Ohland C, Newsome R, Trevino J, Hughes SJ, Reinhard M, Winglee K, Fodor AA, Zajac-Kaye M, Jobin C. Thomas RM, et al. Among authors: pope jl. Carcinogenesis. 2018 Jul 30;39(8):1068-1078. doi: 10.1093/carcin/bgy073. Carcinogenesis. 2018. PMID: 29846515 Free PMC article.
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