Kruczynski A - Search Results

1

Activity of the polyamine-vectorized anti-cancer drug F14512 against pediatric glioma and neuroblastoma cell lines.

Leblond P, Boulet E, Bal-Mahieu C, Pillon A, Kruczynski A, Guilbaud N, Bailly C, Sarrazin T, Lartigau E, Lansiaux A, Meignan S. Leblond P, et al. Among authors: kruczynski a. Invest New Drugs. 2014 Oct;32(5):883-92. doi: 10.1007/s10637-014-0132-3. Epub 2014 Jul 11. Invest New Drugs. 2014. PMID: 25008900

2

Preclinical activity of F14512, designed to target tumors expressing an active polyamine transport system.

Kruczynski A, Vandenberghe I, Pillon A, Pesnel S, Goetsch L, Barret JM, Guminski Y, Le Pape A, Imbert T, Bailly C, Guilbaud N. Kruczynski A, et al. Invest New Drugs. 2011 Feb;29(1):9-21. doi: 10.1007/s10637-009-9328-3. Epub 2009 Sep 24. Invest New Drugs. 2011. PMID: 19777159

3

F14512, a polyamine-vectorized inhibitor of topoisomerase II, exhibits a marked anti-tumor activity in ovarian cancer.

Thibault B, Clement E, Zorza G, Meignan S, Delord JP, Couderc B, Bailly C, Narducci F, Vandenberghe I, Kruczynski A, Guilbaud N, Ferré P, Annereau JP. Thibault B, et al. Among authors: kruczynski a. Cancer Lett. 2016 Jan 1;370(1):10-8. doi: 10.1016/j.canlet.2015.09.006. Epub 2015 Sep 25. Cancer Lett. 2016. PMID: 26404751

4

F14512, a potent antitumor agent targeting topoisomerase II vectored into cancer cells via the polyamine transport system.

Barret JM, Kruczynski A, Vispé S, Annereau JP, Brel V, Guminski Y, Delcros JG, Lansiaux A, Guilbaud N, Imbert T, Bailly C. Barret JM, et al. Among authors: kruczynski a. Cancer Res. 2008 Dec 1;68(23):9845-53. doi: 10.1158/0008-5472.CAN-08-2748. Cancer Res. 2008. PMID: 19047165

5

Cytotoxicity and cell death mechanisms induced by the polyamine-vectorized anti-cancer drug F14512 targeting topoisomerase II.

Brel V, Annereau JP, Vispé S, Kruczynski A, Bailly C, Guilbaud N. Brel V, et al. Among authors: kruczynski a. Biochem Pharmacol. 2011 Dec 15;82(12):1843-52. doi: 10.1016/j.bcp.2011.08.028. Epub 2011 Sep 8. Biochem Pharmacol. 2011. PMID: 21924246

6

F14512, a polyamine-vectorized anti-cancer drug, currently in clinical trials exhibits a marked preclinical anti-leukemic activity.

Kruczynski A, Pillon A, Créancier L, Vandenberghe I, Gomes B, Brel V, Fournier E, Annereau JP, Currie E, Guminski Y, Bonnet D, Bailly C, Guilbaud N. Kruczynski A, et al. Leukemia. 2013 Nov;27(11):2139-48. doi: 10.1038/leu.2013.108. Epub 2013 Apr 9. Leukemia. 2013. PMID: 23568148

7

99mTc-HYNIC-spermine for imaging polyamine transport system-positive tumours: preclinical evaluation.

Pesnel S, Guminski Y, Pillon A, Lerondel S, Imbert T, Guilbaud N, Kruczynski A, Bailly C, Le Pape A. Pesnel S, et al. Among authors: kruczynski a. Eur J Nucl Med Mol Imaging. 2011 Oct;38(10):1832-41. doi: 10.1007/s00259-011-1857-2. Epub 2011 Jun 10. Eur J Nucl Med Mol Imaging. 2011. PMID: 21660624

8

Discovery bioanalysis and in vivo pharmacology as an integrated process: a case study in oncology drug discovery.

Grondin A, Pillon A, Vandenberghe I, Guilbaud N, Kruczynski A, Gomes B. Grondin A, et al. Among authors: kruczynski a. Bioanalysis. 2016 Jul;8(14):1481-98. doi: 10.4155/bio-2016-0062. Epub 2016 Jun 17. Bioanalysis. 2016. PMID: 27314564

9

Synthesis and biological evaluation of (-)-6-O-desmethylcryptopleurine and analogs.

Liéby-Muller F, Marion F, Schmitt P, Annereau JP, Kruczynski A, Guilbaud N, Bailly C. Liéby-Muller F, et al. Among authors: kruczynski a. Bioorg Med Chem Lett. 2015 Jan 15;25(2):184-7. doi: 10.1016/j.bmcl.2014.11.086. Epub 2014 Dec 6. Bioorg Med Chem Lett. 2015. PMID: 25499434

10

Quantitation in bioluminescence imaging by correction of tissue absorption for experimental oncology.

Pesnel S, Pillon A, Créancier L, Guilbaud N, Bailly C, Kruczynski A, Lerondel S, Le Pape A. Pesnel S, et al. Among authors: kruczynski a. Mol Imaging Biol. 2011 Aug;13(4):646-52. doi: 10.1007/s11307-010-0387-9. Mol Imaging Biol. 2011. PMID: 20686859

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