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Regulation of tissue factor pathway inhibitor-2 (TFPI-2) expression by lysine-specific demethylase 1 and 2 (LSD1 and LSD2).
Mino K, Nishimura S, Ninomiya S, Tujii H, Matsumori Y, Tsuchida M, Hosoi M, Koseki K, Wada S, Hasegawa M, Sasaki R, Murakami-Yamaguchi Y, Narita H, Suzuki T, Miyata N, Mizukami T. Mino K, et al. Among authors: miyata n. Biosci Biotechnol Biochem. 2014;78(6):1010-7. doi: 10.1080/09168451.2014.910104. Epub 2014 Jun 13. Biosci Biotechnol Biochem. 2014. PMID: 25036127
Design, synthesis, enzyme-inhibitory activity, and effect on human cancer cells of a novel series of jumonji domain-containing protein 2 histone demethylase inhibitors.
Hamada S, Suzuki T, Mino K, Koseki K, Oehme F, Flamme I, Ozasa H, Itoh Y, Ogasawara D, Komaarashi H, Kato A, Tsumoto H, Nakagawa H, Hasegawa M, Sasaki R, Mizukami T, Miyata N. Hamada S, et al. Among authors: miyata n. J Med Chem. 2010 Aug 12;53(15):5629-38. doi: 10.1021/jm1003655. J Med Chem. 2010. PMID: 20684604
Lysine demethylases inhibitors.
Suzuki T, Miyata N. Suzuki T, et al. Among authors: miyata n. J Med Chem. 2011 Dec 22;54(24):8236-50. doi: 10.1021/jm201048w. Epub 2011 Oct 7. J Med Chem. 2011. PMID: 21955276 Review. No abstract available.
Identification of the KDM2/7 histone lysine demethylase subfamily inhibitor and its antiproliferative activity.
Suzuki T, Ozasa H, Itoh Y, Zhan P, Sawada H, Mino K, Walport L, Ohkubo R, Kawamura A, Yonezawa M, Tsukada Y, Tumber A, Nakagawa H, Hasegawa M, Sasaki R, Mizukami T, Schofield CJ, Miyata N. Suzuki T, et al. Among authors: miyata n. J Med Chem. 2013 Sep 26;56(18):7222-31. doi: 10.1021/jm400624b. Epub 2013 Sep 5. J Med Chem. 2013. PMID: 23964788 Free PMC article.
543 results