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Novel phosphatidylinositol 3-kinase inhibitor NVP-BKM120 induces apoptosis in myeloma cells and shows synergistic anti-myeloma activity with dexamethasone.
Zheng Y, Yang J, Qian J, Zhang L, Lu Y, Li H, Lin H, Lan Y, Liu Z, He J, Hong S, Thomas S, Shah J, Baladandayuthapani V, Kwak LW, Yi Q. Zheng Y, et al. Among authors: lu y. J Mol Med (Berl). 2012 Jun;90(6):695-706. doi: 10.1007/s00109-011-0849-9. Epub 2011 Dec 30. J Mol Med (Berl). 2012. PMID: 22207485 Free PMC article.
Th9 cells promote antitumor immune responses in vivo.
Lu Y, Hong S, Li H, Park J, Hong B, Wang L, Zheng Y, Liu Z, Xu J, He J, Yang J, Qian J, Yi Q. Lu Y, et al. J Clin Invest. 2012 Nov;122(11):4160-71. doi: 10.1172/JCI65459. Epub 2012 Oct 15. J Clin Invest. 2012. PMID: 23064366 Free PMC article.
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