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Mogamulizumab, an anti-CCR4 antibody, targets human T-lymphotropic virus type 1-infected CD8+ and CD4+ T cells to treat associated myelopathy.
Yamauchi J, Coler-Reilly A, Sato T, Araya N, Yagishita N, Ando H, Kunitomo Y, Takahashi K, Tanaka Y, Shibagaki Y, Nishioka K, Nakajima T, Hasegawa Y, Utsunomiya A, Kimura K, Yamano Y. Yamauchi J, et al. J Infect Dis. 2015 Jan 15;211(2):238-48. doi: 10.1093/infdis/jiu438. Epub 2014 Aug 7. J Infect Dis. 2015. PMID: 25104771
Effectiveness of Daily Prednisolone to Slow Progression of Human T-Lymphotropic Virus Type 1-Associated Myelopathy/Tropical Spastic Paraparesis: A Multicenter Retrospective Cohort Study.
Coler-Reilly ALG, Sato T, Matsuzaki T, Nakagawa M, Niino M, Nagai M, Nakamura T, Takenouchi N, Araya N, Yagishita N, Inoue E, Yamano Y. Coler-Reilly ALG, et al. Neurotherapeutics. 2017 Oct;14(4):1084-1094. doi: 10.1007/s13311-017-0533-z. Neurotherapeutics. 2017. PMID: 28536850 Free PMC article.
Mogamulizumab (Anti-CCR4) in HTLV-1-Associated Myelopathy.
Sato T, Coler-Reilly ALG, Yagishita N, Araya N, Inoue E, Furuta R, Watanabe T, Uchimaru K, Matsuoka M, Matsumoto N, Hasegawa Y, Yamano Y. Sato T, et al. N Engl J Med. 2018 Feb 8;378(6):529-538. doi: 10.1056/NEJMoa1704827. N Engl J Med. 2018. PMID: 29414279 Free article. Clinical Trial.
Mortality and risk of progression to adult T cell leukemia/lymphoma in HTLV-1-associated myelopathy/tropical spastic paraparesis.
Nagasaka M, Yamagishi M, Yagishita N, Araya N, Kobayashi S, Makiyama J, Kubokawa M, Yamauchi J, Hasegawa D, Coler-Reilly ALG, Tsutsumi S, Uemura Y, Arai A, Takata A, Inoue E, Hasegawa Y, Watanabe T, Suzuki Y, Uchimaru K, Sato T, Yamano Y. Nagasaka M, et al. Proc Natl Acad Sci U S A. 2020 May 26;117(21):11685-11691. doi: 10.1073/pnas.1920346117. Epub 2020 May 11. Proc Natl Acad Sci U S A. 2020. PMID: 32393644 Free PMC article.
33 results