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Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease.
Lunnon K, Smith R, Hannon E, De Jager PL, Srivastava G, Volta M, Troakes C, Al-Sarraj S, Burrage J, Macdonald R, Condliffe D, Harries LW, Katsel P, Haroutunian V, Kaminsky Z, Joachim C, Powell J, Lovestone S, Bennett DA, Schalkwyk LC, Mill J. Lunnon K, et al. Nat Neurosci. 2014 Sep;17(9):1164-70. doi: 10.1038/nn.3782. Epub 2014 Aug 17. Nat Neurosci. 2014. PMID: 25129077 Free PMC article.
Elucidating distinct molecular signatures of Lewy body dementias.
Harvey J, Pishva E, Chouliaras L, Lunnon K. Harvey J, et al. Among authors: lunnon k. Neurobiol Dis. 2023 Nov;188:106337. doi: 10.1016/j.nbd.2023.106337. Epub 2023 Oct 31. Neurobiol Dis. 2023. PMID: 37918758 Free article. Review.
Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease.
Thambisetty M, Simmons A, Velayudhan L, Hye A, Campbell J, Zhang Y, Wahlund LO, Westman E, Kinsey A, Güntert A, Proitsi P, Powell J, Causevic M, Killick R, Lunnon K, Lynham S, Broadstock M, Choudhry F, Howlett DR, Williams RJ, Sharp SI, Mitchelmore C, Tunnard C, Leung R, Foy C, O'Brien D, Breen G, Furney SJ, Ward M, Kloszewska I, Mecocci P, Soininen H, Tsolaki M, Vellas B, Hodges A, Murphy DG, Parkins S, Richardson JC, Resnick SM, Ferrucci L, Wong DF, Zhou Y, Muehlboeck S, Evans A, Francis PT, Spenger C, Lovestone S. Thambisetty M, et al. Among authors: lunnon k. Arch Gen Psychiatry. 2010 Jul;67(7):739-48. doi: 10.1001/archgenpsychiatry.2010.78. Arch Gen Psychiatry. 2010. PMID: 20603455 Free PMC article.
Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease.
Furney SJ, Simmons A, Breen G, Pedroso I, Lunnon K, Proitsi P, Hodges A, Powell J, Wahlund LO, Kloszewska I, Mecocci P, Soininen H, Tsolaki M, Vellas B, Spenger C, Lathrop M, Shen L, Kim S, Saykin AJ, Weiner MW, Lovestone S; Alzheimer’s Disease Neuroimaging Initiative; AddNeuroMed Consortium. Furney SJ, et al. Among authors: lunnon k. Mol Psychiatry. 2011 Nov;16(11):1130-8. doi: 10.1038/mp.2010.123. Epub 2010 Nov 30. Mol Psychiatry. 2011. PMID: 21116278 Free PMC article.
Mitochondrial dysfunction and immune activation are detectable in early Alzheimer's disease blood.
Lunnon K, Ibrahim Z, Proitsi P, Lourdusamy A, Newhouse S, Sattlecker M, Furney S, Saleem M, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M, Vellas B, Coppola G, Geschwind D, Simmons A, Lovestone S, Dobson R, Hodges A; AddNeuroMed Consortium. Lunnon K, et al. J Alzheimers Dis. 2012;30(3):685-710. doi: 10.3233/JAD-2012-111592. J Alzheimers Dis. 2012. PMID: 22466004 Free article.
Identification of cis-regulatory variation influencing protein abundance levels in human plasma.
Lourdusamy A, Newhouse S, Lunnon K, Proitsi P, Powell J, Hodges A, Nelson SK, Stewart A, Williams S, Kloszewska I, Mecocci P, Soininen H, Tsolaki M, Vellas B, Lovestone S; AddNeuroMed Consortium; Dobson R; Alzheimer's Disease Neuroimaging Initiative. Lourdusamy A, et al. Among authors: lunnon k. Hum Mol Genet. 2012 Aug 15;21(16):3719-26. doi: 10.1093/hmg/dds186. Epub 2012 May 16. Hum Mol Genet. 2012. PMID: 22595970 Free PMC article.
A blood gene expression marker of early Alzheimer's disease.
Lunnon K, Sattlecker M, Furney SJ, Coppola G, Simmons A, Proitsi P, Lupton MK, Lourdusamy A, Johnston C, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M, Vellas B, Geschwind D, Lovestone S, Dobson R, Hodges A; dNeuroMed Consortium. Lunnon K, et al. J Alzheimers Dis. 2013;33(3):737-53. doi: 10.3233/JAD-2012-121363. J Alzheimers Dis. 2013. PMID: 23042217 Free article.
Inflammatory proteins in plasma are associated with severity of Alzheimer's disease.
Leung R, Proitsi P, Simmons A, Lunnon K, Güntert A, Kronenberg D, Pritchard M, Tsolaki M, Mecocci P, Kloszewska I, Vellas B, Soininen H, Wahlund LO, Lovestone S. Leung R, et al. Among authors: lunnon k. PLoS One. 2013 Jun 10;8(6):e64971. doi: 10.1371/journal.pone.0064971. Print 2013. PLoS One. 2013. PMID: 23762274 Free PMC article.
93 results