Dowd KA - Search Results

1

Safety and tolerability of chikungunya virus-like particle vaccine in healthy adults: a phase 1 dose-escalation trial.

Chang LJ, Dowd KA, Mendoza FH, Saunders JG, Sitar S, Plummer SH, Yamshchikov G, Sarwar UN, Hu Z, Enama ME, Bailer RT, Koup RA, Schwartz RM, Akahata W, Nabel GJ, Mascola JR, Pierson TC, Graham BS, Ledgerwood JE; VRC 311 Study Team. Chang LJ, et al. Among authors: dowd ka. Lancet. 2014 Dec 6;384(9959):2046-52. doi: 10.1016/S0140-6736(14)61185-5. Epub 2014 Aug 14. Lancet. 2014. PMID: 25132507 Clinical Trial.

2

Antibody-mediated neutralization of flaviviruses: a reductionist view.

Dowd KA, Pierson TC. Dowd KA, et al. Virology. 2011 Mar 15;411(2):306-15. doi: 10.1016/j.virol.2010.12.020. Epub 2011 Jan 20. Virology. 2011. PMID: 21255816 Free PMC article. Review.

3

A dynamic landscape for antibody binding modulates antibody-mediated neutralization of West Nile virus.

Dowd KA, Jost CA, Durbin AP, Whitehead SS, Pierson TC. Dowd KA, et al. PLoS Pathog. 2011 Jun;7(6):e1002111. doi: 10.1371/journal.ppat.1002111. Epub 2011 Jun 30. PLoS Pathog. 2011. PMID: 21738473 Free PMC article.

4

The infectivity of prM-containing partially mature West Nile virus does not require the activity of cellular furin-like proteases.

Mukherjee S, Lin TY, Dowd KA, Manhart CJ, Pierson TC. Mukherjee S, et al. Among authors: dowd ka. J Virol. 2011 Nov;85(22):12067-72. doi: 10.1128/JVI.05559-11. Epub 2011 Aug 31. J Virol. 2011. PMID: 21880759 Free PMC article.

5

Poorly neutralizing cross-reactive antibodies against the fusion loop of West Nile virus envelope protein protect in vivo via Fcgamma receptor and complement-dependent effector mechanisms.

Vogt MR, Dowd KA, Engle M, Tesh RB, Johnson S, Pierson TC, Diamond MS. Vogt MR, et al. Among authors: dowd ka. J Virol. 2011 Nov;85(22):11567-80. doi: 10.1128/JVI.05859-11. Epub 2011 Sep 14. J Virol. 2011. PMID: 21917960 Free PMC article.

6

A novel approach for the rapid mutagenesis and directed evolution of the structural genes of west nile virus.

Lin TY, Dowd KA, Manhart CJ, Nelson S, Whitehead SS, Pierson TC. Lin TY, et al. Among authors: dowd ka. J Virol. 2012 Apr;86(7):3501-12. doi: 10.1128/JVI.06435-11. Epub 2012 Jan 18. J Virol. 2012. PMID: 22258236 Free PMC article.

7

Structural basis of differential neutralization of DENV-1 genotypes by an antibody that recognizes a cryptic epitope.

Austin SK, Dowd KA, Shrestha B, Nelson CA, Edeling MA, Johnson S, Pierson TC, Diamond MS, Fremont DH. Austin SK, et al. Among authors: dowd ka. PLoS Pathog. 2012;8(10):e1002930. doi: 10.1371/journal.ppat.1002930. Epub 2012 Oct 4. PLoS Pathog. 2012. PMID: 23055922 Free PMC article.

8

Impact of viral attachment factor expression on antibody-mediated neutralization of flaviviruses.

Obara CJ, Dowd KA, Ledgerwood JE, Pierson TC. Obara CJ, et al. Among authors: dowd ka. Virology. 2013 Mar 1;437(1):20-7. doi: 10.1016/j.virol.2012.11.016. Epub 2013 Jan 10. Virology. 2013. PMID: 23312596 Free PMC article.

9

Development of a highly protective combination monoclonal antibody therapy against Chikungunya virus.

Pal P, Dowd KA, Brien JD, Edeling MA, Gorlatov S, Johnson S, Lee I, Akahata W, Nabel GJ, Richter MK, Smit JM, Fremont DH, Pierson TC, Heise MT, Diamond MS. Pal P, et al. Among authors: dowd ka. PLoS Pathog. 2013;9(4):e1003312. doi: 10.1371/journal.ppat.1003312. Epub 2013 Apr 18. PLoS Pathog. 2013. PMID: 23637602 Free PMC article.

10

The Fc region of an antibody impacts the neutralization of West Nile viruses in different maturation states.

Lee PD, Mukherjee S, Edeling MA, Dowd KA, Austin SK, Manhart CJ, Diamond MS, Fremont DH, Pierson TC. Lee PD, et al. Among authors: dowd ka. J Virol. 2013 Dec;87(24):13729-40. doi: 10.1128/JVI.02340-13. Epub 2013 Oct 9. J Virol. 2013. PMID: 24109224 Free PMC article.

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