Villiger TK - Search Results

1

High-throughput nucleoside phosphate monitoring in mammalian cell fed-batch cultivation using quantitative matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

Steinhoff RF, Ivarsson M, Habicher T, Villiger TK, Boertz J, Krismer J, Fagerer SR, Soos M, Morbidelli M, Pabst M, Zenobi R. Steinhoff RF, et al. Among authors: villiger tk. Biotechnol J. 2015 Jan;10(1):190-8. doi: 10.1002/biot.201400292. Epub 2014 Sep 18. Biotechnol J. 2015. PMID: 25139677

2

Development of a Scale-Down Model of hydrodynamic stress to study the performance of an industrial CHO cell line under simulated production scale bioreactor conditions.

Sieck JB, Cordes T, Budach WE, Rhiel MH, Suemeghy Z, Leist C, Villiger TK, Morbidelli M, Soos M. Sieck JB, et al. Among authors: villiger tk. J Biotechnol. 2013 Mar 10;164(1):41-9. doi: 10.1016/j.jbiotec.2012.11.012. Epub 2012 Dec 7. J Biotechnol. 2013. PMID: 23228731

3

Evaluating the impact of cell culture process parameters on monoclonal antibody N-glycosylation.

Ivarsson M, Villiger TK, Morbidelli M, Soos M. Ivarsson M, et al. Among authors: villiger tk. J Biotechnol. 2014 Oct 20;188:88-96. doi: 10.1016/j.jbiotec.2014.08.026. Epub 2014 Aug 28. J Biotechnol. 2014. PMID: 25173615

4

Adaptation for survival: phenotype and transcriptome response of CHO cells to elevated stress induced by agitation and sparging.

Sieck JB, Budach WE, Suemeghy Z, Leist C, Villiger TK, Morbidelli M, Soos M. Sieck JB, et al. Among authors: villiger tk. J Biotechnol. 2014 Nov 10;189:94-103. doi: 10.1016/j.jbiotec.2014.08.042. Epub 2014 Sep 16. J Biotechnol. 2014. PMID: 25218361

5

Analysis of site-specific N-glycan remodeling in the endoplasmic reticulum and the Golgi.

Hang I, Lin CW, Grant OC, Fleurkens S, Villiger TK, Soos M, Morbidelli M, Woods RJ, Gauss R, Aebi M. Hang I, et al. Among authors: villiger tk. Glycobiology. 2015 Dec;25(12):1335-49. doi: 10.1093/glycob/cwv058. Epub 2015 Aug 3. Glycobiology. 2015. PMID: 26240167 Free PMC article.

6

Pilot-scale verification of maximum tolerable hydrodynamic stress for mammalian cell culture.

Neunstoecklin B, Villiger TK, Lucas E, Stettler M, Broly H, Morbidelli M, Soos M. Neunstoecklin B, et al. Among authors: villiger tk. Appl Microbiol Biotechnol. 2016 Apr;100(8):3489-98. doi: 10.1007/s00253-015-7193-x. Epub 2015 Dec 5. Appl Microbiol Biotechnol. 2016. PMID: 26637424

7

High-throughput profiling of nucleotides and nucleotide sugars to evaluate their impact on antibody N-glycosylation.

Villiger TK, Steinhoff RF, Ivarsson M, Solacroup T, Stettler M, Broly H, Krismer J, Pabst M, Zenobi R, Morbidelli M, Soos M. Villiger TK, et al. J Biotechnol. 2016 Jul 10;229:3-12. doi: 10.1016/j.jbiotec.2016.04.039. Epub 2016 Apr 27. J Biotechnol. 2016. PMID: 27131894

8

Controlling the time evolution of mAb N-linked glycosylation, Part I: Microbioreactor experiments.

Villiger TK, Roulet A, Périlleux A, Stettler M, Broly H, Morbidelli M, Soos M. Villiger TK, et al. Biotechnol Prog. 2016 Sep;32(5):1123-1134. doi: 10.1002/btpr.2305. Epub 2016 Jun 27. Biotechnol Prog. 2016. PMID: 27254475

9

Controlling the time evolution of mAb N-linked glycosylation - Part II: Model-based predictions.

Villiger TK, Scibona E, Stettler M, Broly H, Morbidelli M, Soos M. Villiger TK, et al. Biotechnol Prog. 2016 Sep;32(5):1135-1148. doi: 10.1002/btpr.2315. Epub 2016 Jul 1. Biotechnol Prog. 2016. PMID: 27273889

10

Modulation and modeling of monoclonal antibody N-linked glycosylation in mammalian cell perfusion reactors.

Karst DJ, Scibona E, Serra E, Bielser JM, Souquet J, Stettler M, Broly H, Soos M, Morbidelli M, Villiger TK. Karst DJ, et al. Among authors: villiger tk. Biotechnol Bioeng. 2017 Sep;114(9):1978-1990. doi: 10.1002/bit.26315. Epub 2017 May 23. Biotechnol Bioeng. 2017. PMID: 28409838

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