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Modern Multicomponent Reactions for better Drug Syntheses**.
Zarganes-Tzitzikas T, Dömling A. Zarganes-Tzitzikas T, et al. Among authors: domling a. Org Chem Front. 2014 Sep 1;1(7):834-837. doi: 10.1039/C4QO00088A. Org Chem Front. 2014. PMID: 25147729 Free PMC article.
Leuckart-Wallach Route Toward Isocyanides and Some Applications.
Neochoritis CG, Zarganes-Tzitzikas T, Stotani S, Dömling A, Herdtweck E, Khoury K, Dömling A. Neochoritis CG, et al. Among authors: domling a. ACS Comb Sci. 2015 Sep 14;17(9):493-9. doi: 10.1021/acscombsci.5b00066. Epub 2015 Aug 10. ACS Comb Sci. 2015. PMID: 26226194
Multicomponent Reactions, Union of MCRs and Beyond.
Zarganes-Tzitzikas T, Chandgude AL, Dömling A. Zarganes-Tzitzikas T, et al. Among authors: domling a. Chem Rec. 2015 Oct;15(5):981-96. doi: 10.1002/tcr.201500201. Epub 2015 Sep 11. Chem Rec. 2015. PMID: 26455350 Review.
Multicomponent reactions (MCRs), which are located between one- and two-component and polymerization reactions, provide a number of valuable conceptual and synthetic advantages over stepwise sequential approaches towards complex and valuable molecules. To address current l …
Multicomponent reactions (MCRs), which are located between one- and two-component and polymerization reactions, provide a number of v …
Concise Synthesis of Tetrazole-keto-piperazines by Two Consecutive Ugi Reactions.
Zarganes-Tzitzikas T, Patil P, Khoury K, Herdtweck E, Dömling A. Zarganes-Tzitzikas T, et al. Among authors: domling a. European J Org Chem. 2015 Jan;2015(1):51-55. doi: 10.1002/ejoc.201403401. Epub 2014 Nov 17. European J Org Chem. 2015. PMID: 26949370 Free PMC article. No abstract available.
Inhibitors of programmed cell death 1 (PD-1): a patent review (2010-2015).
Zarganes-Tzitzikas T, Konstantinidou M, Gao Y, Krzemien D, Zak K, Dubin G, Holak TA, Dömling A. Zarganes-Tzitzikas T, et al. Among authors: domling a. Expert Opin Ther Pat. 2016 Sep;26(9):973-7. doi: 10.1080/13543776.2016.1206527. Epub 2016 Jul 6. Expert Opin Ther Pat. 2016. PMID: 27367741 Free PMC article. No abstract available.
Bioactive Macrocyclic Inhibitors of the PD-1/PD-L1 Immune Checkpoint.
Magiera-Mularz K, Skalniak L, Zak KM, Musielak B, Rudzinska-Szostak E, Berlicki Ł, Kocik J, Grudnik P, Sala D, Zarganes-Tzitzikas T, Shaabani S, Dömling A, Dubin G, Holak TA. Magiera-Mularz K, et al. Among authors: domling a. Angew Chem Int Ed Engl. 2017 Oct 23;56(44):13732-13735. doi: 10.1002/anie.201707707. Epub 2017 Sep 26. Angew Chem Int Ed Engl. 2017. PMID: 28881104 Free PMC article.
Immune Checkpoint PD-1/PD-L1: Is There Life Beyond Antibodies?
Konstantinidou M, Zarganes-Tzitzikas T, Magiera-Mularz K, Holak TA, Dömling A. Konstantinidou M, et al. Among authors: domling a. Angew Chem Int Ed Engl. 2018 Apr 23;57(18):4840-4848. doi: 10.1002/anie.201710407. Epub 2018 Feb 23. Angew Chem Int Ed Engl. 2018. PMID: 29178534 Free PMC article. Review.
Discovery of chromenes as inhibitors of macrophage migration inhibitory factor.
Kok T, Wapenaar H, Wang K, Neochoritis CG, Zarganes-Tzitzikas T, Proietti G, Eleftheriadis N, Kurpiewska K, Kalinowska-Tłuścik J, Cool RH, Poelarends GJ, Dömling A, Dekker FJ. Kok T, et al. Among authors: domling a. Bioorg Med Chem. 2018 Mar 1;26(5):999-1005. doi: 10.1016/j.bmc.2017.12.032. Epub 2017 Dec 24. Bioorg Med Chem. 2018. PMID: 29428527 Free PMC article.
264 results