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Dithiocarbamate-thiourea hybrids useful as vaginal microbicides also show reverse transcriptase inhibition: design, synthesis, docking and pharmacokinetic studies.
Bala V, Jangir S, Mandalapu D, Gupta S, Chhonker YS, Lal N, Kushwaha B, Chandasana H, Krishna S, Rawat K, Maikhuri JP, Bhatta RS, Siddiqi MI, Tripathi R, Gupta G, Sharma VL. Bala V, et al. Among authors: krishna s. Bioorg Med Chem Lett. 2015 Feb 15;25(4):881-6. doi: 10.1016/j.bmcl.2014.12.062. Epub 2014 Dec 29. Bioorg Med Chem Lett. 2015. PMID: 25592712
N-Alkyl/aryl-4-(3-substituted-3-phenylpropyl)piperazine-1-carbothioamide as dual-action vaginal microbicides with reverse transcriptase inhibition.
Bala V, Mandalapu D, Gupta S, Jangir S, Kushwaha B, Chhonker YS, Chandasana H, Krishna S, Rawat K, Krishna A, Singh M, Sankhwar SN, Shukla PK, Maikhuri JP, Bhatta RS, Siddiqi MI, Tripathi R, Gupta G, Sharma VL. Bala V, et al. Among authors: krishna a, krishna s. Eur J Med Chem. 2015 Aug 28;101:640-50. doi: 10.1016/j.ejmech.2015.07.021. Epub 2015 Jul 13. Eur J Med Chem. 2015. PMID: 26209833
Role of disulfide linkage in action of bis(dialkylaminethiocarbonyl)disulfides as potent double-Edged microbicidal spermicide: Design, synthesis and biology.
Lal N, Jangir S, Bala V, Mandalapu D, Sarswat A, Kumar L, Jain A, Kumar L, Kushwaha B, Pandey AK, Krishna S, Rawat T, Shukla PK, Maikhuri JP, Siddiqi MI, Gupta G, Sharma VL. Lal N, et al. Among authors: krishna s. Eur J Med Chem. 2016 Jun 10;115:275-90. doi: 10.1016/j.ejmech.2016.03.012. Epub 2016 Mar 9. Eur J Med Chem. 2016. PMID: 27084496
1,572 results