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The structural basis of force generation by the mitotic motor kinesin-5.
Goulet A, Behnke-Parks WM, Sindelar CV, Major J, Rosenfeld SS, Moores CA. Goulet A, et al. Among authors: rosenfeld ss. J Biol Chem. 2012 Dec 28;287(53):44654-66. doi: 10.1074/jbc.M112.404228. Epub 2012 Nov 7. J Biol Chem. 2012. PMID: 23135273 Free PMC article.
The mechanism of kinesin inhibition by kinesin-binding protein.
Atherton J, Hummel JJ, Olieric N, Locke J, Peña A, Rosenfeld SS, Steinmetz MO, Hoogenraad CC, Moores CA. Atherton J, et al. Among authors: rosenfeld ss. Elife. 2020 Nov 30;9:e61481. doi: 10.7554/eLife.61481. Elife. 2020. PMID: 33252036 Free PMC article.
Magnesium regulates ADP dissociation from myosin V.
Rosenfeld SS, Houdusse A, Sweeney HL. Rosenfeld SS, et al. J Biol Chem. 2005 Feb 18;280(7):6072-9. doi: 10.1074/jbc.M412717200. Epub 2004 Dec 4. J Biol Chem. 2005. PMID: 15579901 Free article.
Loop L5 acts as a conformational latch in the mitotic kinesin Eg5.
Behnke-Parks WM, Vendome J, Honig B, Maliga Z, Moores C, Rosenfeld SS. Behnke-Parks WM, et al. Among authors: rosenfeld ss. J Biol Chem. 2011 Feb 18;286(7):5242-53. doi: 10.1074/jbc.M110.192930. Epub 2010 Dec 9. J Biol Chem. 2011. PMID: 21148480 Free PMC article.
The unique insert in myosin VI is a structural calcium-calmodulin binding site.
Bahloul A, Chevreux G, Wells AL, Martin D, Nolt J, Yang Z, Chen LQ, Potier N, Van Dorsselaer A, Rosenfeld S, Houdusse A, Sweeney HL. Bahloul A, et al. Proc Natl Acad Sci U S A. 2004 Apr 6;101(14):4787-92. doi: 10.1073/pnas.0306892101. Epub 2004 Mar 22. Proc Natl Acad Sci U S A. 2004. PMID: 15037754 Free PMC article.
The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding.
Bodrug T, Wilson-Kubalek EM, Nithianantham S, Thompson AF, Alfieri A, Gaska I, Major J, Debs G, Inagaki S, Gutierrez P, Gheber L, McKenney RJ, Sindelar CV, Milligan R, Stumpff J, Rosenfeld SS, Forth ST, Al-Bassam J. Bodrug T, et al. Among authors: rosenfeld ss. Elife. 2020 Jan 20;9:e51131. doi: 10.7554/eLife.51131. Elife. 2020. PMID: 31958056 Free PMC article.
136 results