Chen P - Search Results

1

Wuzhi tablet (Schisandra Sphenanthera extract) protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of NRF2-ARE and p53/p21 pathways.

Fan X, Jiang Y, Wang Y, Tan H, Zeng H, Wang Y, Chen P, Qu A, Gonzalez FJ, Huang M, Bi H. Fan X, et al. Among authors: chen p. Drug Metab Dispos. 2014 Dec;42(12):1982-90. doi: 10.1124/dmd.114.059535. Epub 2014 Sep 12. Drug Metab Dispos. 2014. PMID: 25217484 Free PMC article.

2

Low dose of oleanolic acid protects against lithocholic acid-induced cholestasis in mice: potential involvement of nuclear factor-E2-related factor 2-mediated upregulation of multidrug resistance-associated proteins.

Chen P, Zeng H, Wang Y, Fan X, Xu C, Deng R, Zhou X, Bi H, Huang M. Chen P, et al. Drug Metab Dispos. 2014 May;42(5):844-52. doi: 10.1124/dmd.113.056549. Epub 2014 Feb 7. Drug Metab Dispos. 2014. PMID: 24510383

3

Dynamic and coordinated regulation of KEAP1-NRF2-ARE and p53/p21 signaling pathways is associated with acetaminophen injury responsive liver regeneration.

Fan X, Chen P, Tan H, Zeng H, Jiang Y, Wang Y, Wang Y, Hou X, Bi H, Huang M. Fan X, et al. Among authors: chen p. Drug Metab Dispos. 2014 Sep;42(9):1532-9. doi: 10.1124/dmd.114.059394. Epub 2014 Jul 7. Drug Metab Dispos. 2014. PMID: 25002747

4

Schisandrol B protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of liver regeneration.

Jiang Y, Fan X, Wang Y, Chen P, Zeng H, Tan H, Gonzalez FJ, Huang M, Bi H. Jiang Y, et al. Among authors: chen p. Toxicol Sci. 2015 Jan;143(1):107-15. doi: 10.1093/toxsci/kfu216. Epub 2014 Oct 14. Toxicol Sci. 2015. PMID: 25319358 Free PMC article.

5

Resveratrol suppresses the inducible expression of CYP3A4 through the pregnane X receptor.

Deng R, Xu C, Chen X, Chen P, Wang Y, Zhou X, Jin J, Niu L, Ying M, Huang M, Bi H. Deng R, et al. Among authors: chen p, chen x. J Pharmacol Sci. 2014;126(2):146-54. doi: 10.1254/jphs.14132fp. J Pharmacol Sci. 2014. PMID: 25341566 Free article.

6

Therapeutic efficacy of Wuzhi tablet (Schisandra sphenanthera Extract) on acetaminophen-induced hepatotoxicity through a mechanism distinct from N-acetylcysteine.

Fan X, Chen P, Jiang Y, Wang Y, Tan H, Zeng H, Wang Y, Qu A, Gonzalez FJ, Huang M, Bi H. Fan X, et al. Among authors: chen p. Drug Metab Dispos. 2015 Mar;43(3):317-24. doi: 10.1124/dmd.114.062067. Epub 2014 Dec 22. Drug Metab Dispos. 2015. PMID: 25534769 Free PMC article.

7

Effects of nicotinamide N-methyltransferase on PANC-1 cells proliferation, metastatic potential and survival under metabolic stress.

Yu T, Wang YT, Chen P, Li YH, Chen YX, Zeng H, Yu AM, Huang M, Bi HC. Yu T, et al. Among authors: chen yx, chen p. Cell Physiol Biochem. 2015;35(2):710-21. doi: 10.1159/000369731. Epub 2015 Jan 28. Cell Physiol Biochem. 2015. PMID: 25592232 Free article.

8

Hepato-protective effects of six schisandra lignans on acetaminophen-induced liver injury are partially associated with the inhibition of CYP-mediated bioactivation.

Jiang Y, Fan X, Wang Y, Tan H, Chen P, Zeng H, Huang M, Bi H. Jiang Y, et al. Among authors: chen p. Chem Biol Interact. 2015 Apr 25;231:83-9. doi: 10.1016/j.cbi.2015.02.022. Epub 2015 Mar 6. Chem Biol Interact. 2015. PMID: 25753323

9

Hepato-protective effect of resveratrol against acetaminophen-induced liver injury is associated with inhibition of CYP-mediated bioactivation and regulation of SIRT1-p53 signaling pathways.

Wang Y, Jiang Y, Fan X, Tan H, Zeng H, Wang Y, Chen P, Huang M, Bi H. Wang Y, et al. Among authors: chen p. Toxicol Lett. 2015 Jul 16;236(2):82-9. doi: 10.1016/j.toxlet.2015.05.001. Epub 2015 May 5. Toxicol Lett. 2015. PMID: 25956474

10

Oleanolic acid attenuates obstructive cholestasis in bile duct-ligated mice, possibly via activation of NRF2-MRPs and FXR antagonism.

Chen P, Li J, Fan X, Zeng H, Deng R, Li D, Huang M, Bi H. Chen P, et al. Eur J Pharmacol. 2015 Oct 15;765:131-9. doi: 10.1016/j.ejphar.2015.08.029. Epub 2015 Aug 20. Eur J Pharmacol. 2015. PMID: 26297978

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