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Wuzhi tablet (Schisandra Sphenanthera extract) protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of NRF2-ARE and p53/p21 pathways.
Fan X, Jiang Y, Wang Y, Tan H, Zeng H, Wang Y, Chen P, Qu A, Gonzalez FJ, Huang M, Bi H. Fan X, et al. Among authors: huang m. Drug Metab Dispos. 2014 Dec;42(12):1982-90. doi: 10.1124/dmd.114.059535. Epub 2014 Sep 12. Drug Metab Dispos. 2014. PMID: 25217484 Free PMC article.
Small interfering RNA-mediated silencing of cytochrome P450 3A4 gene.
Chen J, Yang XX, Huang M, Hu ZP, He M, Duan W, Chan E, Sheu FS, Chen X, Zhou SF. Chen J, et al. Among authors: huang m. Drug Metab Dispos. 2006 Sep;34(9):1650-7. doi: 10.1124/dmd.106.009837. Epub 2006 Jun 7. Drug Metab Dispos. 2006. PMID: 16760227
Determination of CH330331, a novel 4-anilinoquinazoline inhibitor of epidermal growth factor receptor tyrosine kinase, in human Caco-2 monolayers by high performance liquid chromatography with ultraviolet detection: application to a trans-epithelial transport study.
Sun HY, Guan S, Bi HC, Su QB, Huang WL, Chowbay B, Huang M, Chen X, Li CG, Zhou SF. Sun HY, et al. Among authors: huang m, huang wl. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Jul 1;854(1-2):320-7. doi: 10.1016/j.jchromb.2007.03.052. Epub 2007 Apr 19. J Chromatogr B Analyt Technol Biomed Life Sci. 2007. PMID: 17467348
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