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Page 1
Specific molecular mutation patterns delineate chronic neutrophilic leukemia, atypical chronic myeloid leukemia, and chronic myelomonocytic leukemia.
Meggendorfer M, Haferlach T, Alpermann T, Jeromin S, Haferlach C, Kern W, Schnittger S. Meggendorfer M, et al. Among authors: alpermann t. Haematologica. 2014 Dec;99(12):e244-6. doi: 10.3324/haematol.2014.113159. Epub 2014 Sep 19. Haematologica. 2014. PMID: 25239264 Free PMC article. No abstract available.
CDKN1B, encoding the cyclin-dependent kinase inhibitor 1B (p27), is located in the minimally deleted region of 12p abnormalities in myeloid malignancies and its low expression is a favorable prognostic marker in acute myeloid leukemia.
Haferlach C, Bacher U, Kohlmann A, Schindela S, Alpermann T, Kern W, Schnittger S, Haferlach T. Haferlach C, et al. Among authors: alpermann t. Haematologica. 2011 Jun;96(6):829-36. doi: 10.3324/haematol.2010.035584. Epub 2011 Mar 21. Haematologica. 2011. PMID: 21422114 Free PMC article.
Prognostic relevance of RUNX1 mutations in T-cell acute lymphoblastic leukemia.
Grossmann V, Kern W, Harbich S, Alpermann T, Jeromin S, Schnittger S, Haferlach C, Haferlach T, Kohlmann A. Grossmann V, et al. Among authors: alpermann t. Haematologica. 2011 Dec;96(12):1874-7. doi: 10.3324/haematol.2011.043919. Epub 2011 Aug 9. Haematologica. 2011. PMID: 21828118 Free PMC article.
Molecular analyses of 15,542 patients with suspected BCR-ABL1-negative myeloproliferative disorders allow to develop a stepwise diagnostic workflow.
Schnittger S, Bacher U, Eder C, Dicker F, Alpermann T, Grossmann V, Kohlmann A, Kern W, Haferlach C, Haferlach T. Schnittger S, et al. Among authors: alpermann t. Haematologica. 2012 Oct;97(10):1582-5. doi: 10.3324/haematol.2012.064683. Epub 2012 Apr 17. Haematologica. 2012. PMID: 22511494 Free PMC article.
SRSF2 mutations in 275 cases with chronic myelomonocytic leukemia (CMML).
Meggendorfer M, Roller A, Haferlach T, Eder C, Dicker F, Grossmann V, Kohlmann A, Alpermann T, Yoshida K, Ogawa S, Koeffler HP, Kern W, Haferlach C, Schnittger S. Meggendorfer M, et al. Among authors: alpermann t. Blood. 2012 Oct 11;120(15):3080-8. doi: 10.1182/blood-2012-01-404863. Epub 2012 Aug 23. Blood. 2012. PMID: 22919025 Free PMC article.
Karyotype evolution and acquisition of FLT3 or RAS pathway alterations drive progression of myelodysplastic syndrome to acute myeloid leukemia.
Meggendorfer M, de Albuquerque A, Nadarajah N, Alpermann T, Kern W, Steuer K, Perglerová K, Haferlach C, Schnittger S, Haferlach T. Meggendorfer M, et al. Among authors: alpermann t. Haematologica. 2015 Dec;100(12):e487-90. doi: 10.3324/haematol.2015.127985. Epub 2015 Aug 20. Haematologica. 2015. PMID: 26294738 Free PMC article. No abstract available.
Molecular subtypes of NPM1 mutations have different clinical profiles, specific patterns of accompanying molecular mutations and varying outcomes in intermediate risk acute myeloid leukemia.
Alpermann T, Schnittger S, Eder C, Dicker F, Meggendorfer M, Kern W, Schmid C, Aul C, Staib P, Wendtner CM, Schmitz N, Haferlach C, Haferlach T. Alpermann T, et al. Haematologica. 2016 Feb;101(2):e55-8. doi: 10.3324/haematol.2015.133819. Epub 2015 Oct 15. Haematologica. 2016. PMID: 26471486 Free PMC article. No abstract available.
105 results