Holtmann H - Search Results

1

Hyperactivation of mTORC1 and mTORC2 by multiple oncogenic events causes addiction to eIF4E-dependent mRNA translation in T-cell leukemia.

Schwarzer A, Holtmann H, Brugman M, Meyer J, Schauerte C, Zuber J, Steinemann D, Schlegelberger B, Li Z, Baum C. Schwarzer A, et al. Among authors: holtmann h. Oncogene. 2015 Jul;34(27):3593-604. doi: 10.1038/onc.2014.290. Epub 2014 Sep 22. Oncogene. 2015. PMID: 25241901

2

Interleukin-17 (IL-17) and IL-1 activate translation of overlapping sets of mRNAs, including that of the negative regulator of inflammation, MCPIP1.

Dhamija S, Winzen R, Doerrie A, Behrens G, Kuehne N, Schauerte C, Neumann E, Dittrich-Breiholz O, Kracht M, Holtmann H. Dhamija S, et al. Among authors: holtmann h. J Biol Chem. 2013 Jun 28;288(26):19250-9. doi: 10.1074/jbc.M113.452649. Epub 2013 May 8. J Biol Chem. 2013. PMID: 23658019 Free PMC article.

3

The p38/MK2-driven exchange between tristetraprolin and HuR regulates AU-rich element-dependent translation.

Tiedje C, Ronkina N, Tehrani M, Dhamija S, Laass K, Holtmann H, Kotlyarov A, Gaestel M. Tiedje C, et al. Among authors: holtmann h. PLoS Genet. 2012 Sep;8(9):e1002977. doi: 10.1371/journal.pgen.1002977. Epub 2012 Sep 27. PLoS Genet. 2012. PMID: 23028373 Free PMC article.

4

IL-1-induced post-transcriptional mechanisms target overlapping translational silencing and destabilizing elements in IκBζ mRNA.

Dhamija S, Doerrie A, Winzen R, Dittrich-Breiholz O, Taghipour A, Kuehne N, Kracht M, Holtmann H. Dhamija S, et al. Among authors: holtmann h. J Biol Chem. 2010 Sep 17;285(38):29165-78. doi: 10.1074/jbc.M110.146365. Epub 2010 Jul 15. J Biol Chem. 2010. PMID: 20634286 Free PMC article.

5

The role of mammalian MAPK signaling in regulation of cytokine mRNA stability and translation.

Tiedje C, Holtmann H, Gaestel M. Tiedje C, et al. Among authors: holtmann h. J Interferon Cytokine Res. 2014 Apr;34(4):220-32. doi: 10.1089/jir.2013.0146. J Interferon Cytokine Res. 2014. PMID: 24697200 Review.

6

Multiple control of interleukin-8 gene expression.

Hoffmann E, Dittrich-Breiholz O, Holtmann H, Kracht M. Hoffmann E, et al. Among authors: holtmann h. J Leukoc Biol. 2002 Nov;72(5):847-55. J Leukoc Biol. 2002. PMID: 12429706 Review.

7

Selective up-regulation of the 75-kDa tumor necrosis factor (TNF) receptor and its mRNA by TNF and IL-1.

Winzen R, Wallach D, Kemper O, Resch K, Holtmann H. Winzen R, et al. Among authors: holtmann h. J Immunol. 1993 May 15;150(10):4346-53. J Immunol. 1993. PMID: 8387093

8

Interleukin-1 activates synthesis of interleukin-6 by interfering with a KH-type splicing regulatory protein (KSRP)-dependent translational silencing mechanism.

Dhamija S, Kuehne N, Winzen R, Doerrie A, Dittrich-Breiholz O, Thakur BK, Kracht M, Holtmann H. Dhamija S, et al. Among authors: holtmann h. J Biol Chem. 2011 Sep 23;286(38):33279-88. doi: 10.1074/jbc.M111.264754. Epub 2011 Jul 27. J Biol Chem. 2011. PMID: 21795706 Free PMC article.

9

The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism.

Winzen R, Kracht M, Ritter B, Wilhelm A, Chen CY, Shyu AB, Müller M, Gaestel M, Resch K, Holtmann H. Winzen R, et al. Among authors: holtmann h. EMBO J. 1999 Sep 15;18(18):4969-80. doi: 10.1093/emboj/18.18.4969. EMBO J. 1999. PMID: 10487749 Free PMC article.

10

Affinity purification of ARE-binding proteins identifies polyA-binding protein 1 as a potential substrate in MK2-induced mRNA stabilization.

Bollig F, Winzen R, Gaestel M, Kostka S, Resch K, Holtmann H. Bollig F, et al. Among authors: holtmann h. Biochem Biophys Res Commun. 2003 Feb 14;301(3):665-70. doi: 10.1016/s0006-291x(03)00015-9. Biochem Biophys Res Commun. 2003. PMID: 12565831

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