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The concordance between nonclinical and phase I clinical cardiovascular assessment from a cross-company data sharing initiative.
Ewart L, Aylott M, Deurinck M, Engwall M, Gallacher DJ, Geys H, Jarvis P, Ju H, Leishman D, Leong L, McMahon N, Mead A, Milliken P, Suter W, Teisman A, Van Ammel K, Vargas HM, Wallis R, Valentin JP. Ewart L, et al. Among authors: aylott m. Toxicol Sci. 2014 Dec;142(2):427-35. doi: 10.1093/toxsci/kfu198. Epub 2014 Sep 21. Toxicol Sci. 2014. PMID: 25246669
Evaluating Associations Between Nonclinical Cardiovascular Functional Endpoints and Repeat-dose Cardiovascular Toxicity in the Beagle Dog: A Cross-company Initiative.
Milliken P, Aylott M, Edmunds N, Engle S, Ewart L, Fleurance R, Guffroy M, Hargreaves A, Heinz-Taheny K, Kirk S, Leishman D, Leong L, McMahon N, Valentin JP, Watson D, Wallis R, Clements P. Milliken P, et al. Among authors: aylott m. Toxicol Sci. 2020 Jul 1;176(1):224-235. doi: 10.1093/toxsci/kfaa051. Toxicol Sci. 2020. PMID: 32298455
Engineered hexavalent Fc proteins with enhanced Fc-gamma receptor avidity provide insights into immune-complex interactions.
Rowley TF, Peters SJ, Aylott M, Griffin R, Davies NL, Healy LJ, Cutler RM, Eddleston A, Pither TL, Sopp JM, Zaccheo O, Fossati G, Cain K, Ventom AM, Hailu H, Ward EJ, Sherington J, Brennan FR, Fallah-Arani F, Humphreys DP. Rowley TF, et al. Among authors: aylott m. Commun Biol. 2018 Sep 14;1:146. doi: 10.1038/s42003-018-0149-9. eCollection 2018. Commun Biol. 2018. PMID: 30272022 Free PMC article.
32 results