Sevenich L - Search Results

1

Distinct functions of macrophage-derived and cancer cell-derived cathepsin Z combine to promote tumor malignancy via interactions with the extracellular matrix.

Akkari L, Gocheva V, Kester JC, Hunter KE, Quick ML, Sevenich L, Wang HW, Peters C, Tang LH, Klimstra DS, Reinheckel T, Joyce JA. Akkari L, et al. Among authors: sevenich l. Genes Dev. 2014 Oct 1;28(19):2134-50. doi: 10.1101/gad.249599.114. Genes Dev. 2014. PMID: 25274726 Free PMC article.

2

Human cathepsin L rescues the neurodegeneration and lethality in cathepsin B/L double-deficient mice.

Sevenich L, Pennacchio LA, Peters C, Reinheckel T. Sevenich L, et al. Biol Chem. 2006 Jul;387(7):885-91. doi: 10.1515/BC.2006.112. Biol Chem. 2006. PMID: 16913838 Free article.

3

Reduced tumour cell proliferation and delayed development of high-grade mammary carcinomas in cathepsin B-deficient mice.

Vasiljeva O, Korovin M, Gajda M, Brodoefel H, Bojic L, Krüger A, Schurigt U, Sevenich L, Turk B, Peters C, Reinheckel T. Vasiljeva O, et al. Among authors: sevenich l. Oncogene. 2008 Jul 10;27(30):4191-9. doi: 10.1038/onc.2008.59. Epub 2008 Mar 17. Oncogene. 2008. PMID: 18345026

4

Trial of the cysteine cathepsin inhibitor JPM-OEt on early and advanced mammary cancer stages in the MMTV-PyMT-transgenic mouse model.

Schurigt U, Sevenich L, Vannier C, Gajda M, Schwinde A, Werner F, Stahl A, von Elverfeldt D, Becker AK, Bogyo M, Peters C, Reinheckel T. Schurigt U, et al. Among authors: sevenich l. Biol Chem. 2008 Aug;389(8):1067-74. doi: 10.1515/BC.2008.115. Biol Chem. 2008. PMID: 18710344

5

Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice.

Sevenich L, Schurigt U, Sachse K, Gajda M, Werner F, Müller S, Vasiljeva O, Schwinde A, Klemm N, Deussing J, Peters C, Reinheckel T. Sevenich L, et al. Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2497-502. doi: 10.1073/pnas.0907240107. Epub 2010 Jan 21. Proc Natl Acad Sci U S A. 2010. PMID: 20133781 Free PMC article.

6

Expression of human cathepsin L or human cathepsin V in mouse thymus mediates positive selection of T helper cells in cathepsin L knock-out mice.

Sevenich L, Hagemann S, Stoeckle C, Tolosa E, Peters C, Reinheckel T. Sevenich L, et al. Biochimie. 2010 Nov;92(11):1674-80. doi: 10.1016/j.biochi.2010.03.014. Epub 2010 Mar 25. Biochimie. 2010. PMID: 20347002

7

Transgenic expression of human cathepsin B promotes progression and metastasis of polyoma-middle-T-induced breast cancer in mice.

Sevenich L, Werner F, Gajda M, Schurigt U, Sieber C, Müller S, Follo M, Peters C, Reinheckel T. Sevenich L, et al. Oncogene. 2011 Jan 6;30(1):54-64. doi: 10.1038/onc.2010.387. Epub 2010 Sep 6. Oncogene. 2011. PMID: 20818432

8

Decreased arthritis severity in cathepsin L-deficient mice is attributed to an impaired T helper cell compartment.

Schurigt U, Eilenstein R, Gajda M, Leipner C, Sevenich L, Reinheckel T, Peters C, Wiederanders B, Bräuer R. Schurigt U, et al. Among authors: sevenich l. Inflamm Res. 2012 Sep;61(9):1021-9. doi: 10.1007/s00011-012-0495-x. Epub 2012 Jun 7. Inflamm Res. 2012. PMID: 22674323

9

CSF-1R inhibition alters macrophage polarization and blocks glioma progression.

Pyonteck SM, Akkari L, Schuhmacher AJ, Bowman RL, Sevenich L, Quail DF, Olson OC, Quick ML, Huse JT, Teijeiro V, Setty M, Leslie CS, Oei Y, Pedraza A, Zhang J, Brennan CW, Sutton JC, Holland EC, Daniel D, Joyce JA. Pyonteck SM, et al. Among authors: sevenich l. Nat Med. 2013 Oct;19(10):1264-72. doi: 10.1038/nm.3337. Epub 2013 Sep 22. Nat Med. 2013. PMID: 24056773 Free PMC article.

10

Cell type-dependent pathogenic functions of overexpressed human cathepsin B in murine breast cancer progression.

Bengsch F, Buck A, Günther SC, Seiz JR, Tacke M, Pfeifer D, von Elverfeldt D, Sevenich L, Hillebrand LE, Kern U, Sameni M, Peters C, Sloane BF, Reinheckel T. Bengsch F, et al. Among authors: sevenich l. Oncogene. 2014 Sep 4;33(36):4474-84. doi: 10.1038/onc.2013.395. Epub 2013 Sep 30. Oncogene. 2014. PMID: 24077280 Free PMC article.

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