Burrell-Saward H - Search Results

1

A sensitive and reproducible in vivo imaging mouse model for evaluation of drugs against late-stage human African trypanosomiasis.

Burrell-Saward H, Rodgers J, Bradley B, Croft SL, Ward TH. Burrell-Saward H, et al. J Antimicrob Chemother. 2015 Feb;70(2):510-7. doi: 10.1093/jac/dku393. Epub 2014 Oct 8. J Antimicrob Chemother. 2015. PMID: 25298516

2

Highly sensitive in vivo imaging of Trypanosoma brucei expressing "red-shifted" luciferase.

McLatchie AP, Burrell-Saward H, Myburgh E, Lewis MD, Ward TH, Mottram JC, Croft SL, Kelly JM, Taylor MC. McLatchie AP, et al. Among authors: burrell saward h. PLoS Negl Trop Dis. 2013 Nov 21;7(11):e2571. doi: 10.1371/journal.pntd.0002571. eCollection 2013 Nov. PLoS Negl Trop Dis. 2013. PMID: 24278497 Free PMC article.

3

Bioluminescence Imaging to Detect Late Stage Infection of African Trypanosomiasis.

Burrell-Saward H, Ward TH. Burrell-Saward H, et al. J Vis Exp. 2016 May 18;(111):54032. doi: 10.3791/54032. J Vis Exp. 2016. PMID: 27284970 Free PMC article.

4

Dose-dependent effect and pharmacokinetics of fexinidazole and its metabolites in a mouse model of human African trypanosomiasis.

Burrell-Saward H, Harris AJ, de LaFlor R, Sallam H, Alavijeh MS, Ward TH, Croft SL. Burrell-Saward H, et al. Int J Antimicrob Agents. 2017 Aug;50(2):203-209. doi: 10.1016/j.ijantimicag.2017.01.038. Epub 2017 May 25. Int J Antimicrob Agents. 2017. PMID: 28552771

5

Antileishmanial activity, uptake, and biodistribution of an amphotericin B and poly(α-Glutamic Acid) complex.

Mohamed-Ahmed AH, Seifert K, Yardley V, Burrell-Saward H, Brocchini S, Croft SL. Mohamed-Ahmed AH, et al. Antimicrob Agents Chemother. 2013 Oct;57(10):4608-14. doi: 10.1128/AAC.02343-12. Epub 2013 Jun 24. Antimicrob Agents Chemother. 2013. PMID: 23796924 Free PMC article.

6

Drug reformulation for a neglected disease. The NANOHAT project to develop a safer more effective sleeping sickness drug.

Sanderson L, da Silva M, Sekhar GN, Brown RC, Burrell-Saward H, Fidanboylu M, Liu B, Dailey LA, Dreiss CA, Lorenz C, Christie M, Persaud SJ, Yardley V, Croft SL, Valero M, Thomas SA. Sanderson L, et al. Among authors: burrell saward h. PLoS Negl Trop Dis. 2021 Apr 15;15(4):e0009276. doi: 10.1371/journal.pntd.0009276. eCollection 2021 Apr. PLoS Negl Trop Dis. 2021. PMID: 33857146 Free PMC article.

7

Bioluminescence imaging of chronic Trypanosoma cruzi infections reveals tissue-specific parasite dynamics and heart disease in the absence of locally persistent infection.

Lewis MD, Fortes Francisco A, Taylor MC, Burrell-Saward H, McLatchie AP, Miles MA, Kelly JM. Lewis MD, et al. Among authors: burrell saward h. Cell Microbiol. 2014 Sep;16(9):1285-300. doi: 10.1111/cmi.12297. Epub 2014 May 1. Cell Microbiol. 2014. PMID: 24712539 Free PMC article.

8

Decoding the network of Trypanosoma brucei proteins that determines sensitivity to apolipoprotein-L1.

Currier RB, Cooper A, Burrell-Saward H, MacLeod A, Alsford S. Currier RB, et al. Among authors: burrell saward h. PLoS Pathog. 2018 Jan 18;14(1):e1006855. doi: 10.1371/journal.ppat.1006855. eCollection 2018 Jan. PLoS Pathog. 2018. PMID: 29346416 Free PMC article.

9

Synthesis and antitrypanosomal activities of novel pyridylchalcones.

Bhambra AS, Ruparelia KC, Tan HL, Tasdemir D, Burrell-Saward H, Yardley V, Beresford KJM, Arroo RRJ. Bhambra AS, et al. Among authors: burrell saward h. Eur J Med Chem. 2017 Mar 10;128:213-218. doi: 10.1016/j.ejmech.2017.01.027. Epub 2017 Jan 23. Eur J Med Chem. 2017. PMID: 28189085

10

Design, synthesis and antitrypanosomal activities of 2,6-disubstituted-4,5,7-trifluorobenzothiophenes.

Bhambra AS, Edgar M, Elsegood MRJ, Li Y, Weaver GW, Arroo RRJ, Yardley V, Burrell-Saward H, Krystof V. Bhambra AS, et al. Among authors: burrell saward h. Eur J Med Chem. 2016 Jan 27;108:347-353. doi: 10.1016/j.ejmech.2015.11.043. Epub 2015 Nov 30. Eur J Med Chem. 2016. PMID: 26698538 Free article.

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