Karpen SJ - Search Results

1

P2Y2 purinergic receptor activation is essential for efficient hepatocyte proliferation in response to partial hepatectomy.

Tackett BC, Sun H, Mei Y, Maynard JP, Cheruvu S, Mani A, Hernandez-Garcia A, Vigneswaran N, Karpen SJ, Thevananther S. Tackett BC, et al. Among authors: karpen sj. Am J Physiol Gastrointest Liver Physiol. 2014 Dec 1;307(11):G1073-87. doi: 10.1152/ajpgi.00092.2014. Epub 2014 Oct 9. Am J Physiol Gastrointest Liver Physiol. 2014. PMID: 25301185 Free PMC article.

2

Hypertrophic cardiomyopathy and dysregulation of cardiac energetics in a mouse model of biliary fibrosis.

Desai MS, Shabier Z, Taylor M, Lam F, Thevananther S, Kosters A, Karpen SJ. Desai MS, et al. Among authors: karpen sj. Hepatology. 2010 Jun;51(6):2097-107. doi: 10.1002/hep.23585. Hepatology. 2010. PMID: 20512997 Free PMC article.

3

Gene-specific alterations of hepatic gene expression by ligand activation or hepatocyte-selective inhibition of retinoid X receptor-α signalling during inflammation.

Kosters A, Tian F, Wan YJ, Karpen SJ. Kosters A, et al. Among authors: karpen sj. Liver Int. 2012 Feb;32(2):321-30. doi: 10.1111/j.1478-3231.2011.02664.x. Epub 2011 Nov 1. Liver Int. 2012. PMID: 22098603 Free PMC article.

4

Cardiomyopathy reverses with recovery of liver injury, cholestasis and cholanemia in mouse model of biliary fibrosis.

Desai MS, Eblimit Z, Thevananther S, Kosters A, Moore DD, Penny DJ, Karpen SJ. Desai MS, et al. Among authors: karpen sj. Liver Int. 2015 Apr;35(4):1464-77. doi: 10.1111/liv.12438. Epub 2014 Jan 12. Liver Int. 2015. PMID: 24330504 Free PMC article.

5

TGR5 activation induces cytoprotective changes in the heart and improves myocardial adaptability to physiologic, inotropic, and pressure-induced stress in mice.

Eblimit Z, Thevananther S, Karpen SJ, Taegtmeyer H, Moore DD, Adorini L, Penny DJ, Desai MS. Eblimit Z, et al. Among authors: karpen sj. Cardiovasc Ther. 2018 Oct;36(5):e12462. doi: 10.1111/1755-5922.12462. Epub 2018 Aug 22. Cardiovasc Ther. 2018. PMID: 30070769 Free PMC article.

6

Curcumin improves sclerosing cholangitis in Mdr2-/- mice by inhibition of cholangiocyte inflammatory response and portal myofibroblast proliferation.

Baghdasaryan A, Claudel T, Kosters A, Gumhold J, Silbert D, Thüringer A, Leski K, Fickert P, Karpen SJ, Trauner M. Baghdasaryan A, et al. Among authors: karpen sj. Gut. 2010 Apr;59(4):521-30. doi: 10.1136/gut.2009.186528. Gut. 2010. PMID: 20332524 Free PMC article.

7

The role of inflammation in cholestasis: clinical and basic aspects.

Kosters A, Karpen SJ. Kosters A, et al. Among authors: karpen sj. Semin Liver Dis. 2010 May;30(2):186-94. doi: 10.1055/s-0030-1253227. Epub 2010 Apr 26. Semin Liver Dis. 2010. PMID: 20422500 Free PMC article. Review.

8

Inflammatory mediators increase SUMOylation of retinoid X receptor α in a c-Jun N-terminal kinase-dependent manner in human hepatocellular carcinoma cells.

Schneider Aguirre R, Karpen SJ. Schneider Aguirre R, et al. Among authors: karpen sj. Mol Pharmacol. 2013 Aug;84(2):218-26. doi: 10.1124/mol.113.085555. Epub 2013 May 20. Mol Pharmacol. 2013. PMID: 23690070 Free PMC article.

9

Impaired bile acid handling and aggravated liver injury in mice expressing a hepatocyte-specific RXRα variant lacking the DNA-binding domain.

Kosters A, Felix JC, Desai MS, Karpen SJ. Kosters A, et al. Among authors: karpen sj. J Hepatol. 2014 Feb;60(2):362-9. doi: 10.1016/j.jhep.2013.09.026. Epub 2013 Oct 10. J Hepatol. 2014. PMID: 24120911 Free PMC article.

10

Sexually dimorphic genome-wide binding of retinoid X receptor alpha (RXRα) determines male-female differences in the expression of hepatic lipid processing genes in mice.

Kosters A, Sun D, Wu H, Tian F, Felix JC, Li W, Karpen SJ. Kosters A, et al. Among authors: karpen sj. PLoS One. 2013 Aug 19;8(8):e71538. doi: 10.1371/journal.pone.0071538. eCollection 2013. PLoS One. 2013. PMID: 23977068 Free PMC article.

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